: any of a breed of tall massive powerful smooth-coated dogs
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Spreading joy with Wally, his boxer, Great Dane, hound mix, or his grand-dog, Aja — who are both certified therapy dogs — Derene visits schools, active living communities and other locations.—Lesly Gregory, AJC.com, 18 Mar. 2026 In spite of the frigid weather, pavilions hosting the more popular breeds—the pug, the Doberman pinscher, the Great Dane, the St. Bernard—were packed.—John Seabrook, New Yorker, 16 Mar. 2026 The Great Dane puppy at the center of the mystery is, of course, Scooby-Doo himself.—Hanna Wickes, Charlotte Observer, 24 Feb. 2026 However, a Great Dane–Poodle mix like Oakley is still relatively rare, but doodle-type dogs overall are increasingly showing up in shelters.—Lucy Notarantonio, MSNBC Newsweek, 9 Dec. 2025 See All Example Sentences for Great Dane