: a lipoprotein of blood plasma that is composed of a high proportion of protein with little triglyceride and cholesterol and that is correlated with reduced risk of atherosclerosis : good cholesterol compare ldl

Examples of HDL in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Compared to a placebo, grapes have improved blood lipids by decreasing total cholesterol and increasing HDL cholesterol. Brittany Lubeck, Verywell Health, 16 Dec. 2025 Supplementing with vitamin D can lower LDL and total cholesterol, but doesn't affect HDL cholesterol. Emmanuella Ogbonna, Health, 11 Dec. 2025 Low-carb diets improved triglycerides, HDL, blood pressure, inflammation, and weight, with LDL cholesterol rising more modestly than on a keto diet. Emily Kay Votruba, EverydayHealth.com, 3 Dec. 2025 Male mice also saw an increase in good cholesterol (HDL) and decrease in bad cholesterol (LDL), while female mice experienced a decrease in insulin levels. New Atlas, 14 Nov. 2025 See All Example Sentences for HDL

Word History

Etymology

high-density lipoprotein

First Known Use

1954, in the meaning defined above

Time Traveler
The first known use of HDL was in 1954

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Cite this Entry

“HDL.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/HDL. Accessed 31 Dec. 2025.

Medical Definition

: a lipoprotein of blood plasma that is composed of a high proportion of protein with little triglyceride and cholesterol and that is associated with decreased probability of developing atherosclerosis

called also alpha-lipoprotein, good cholesterol, high-density lipoprotein

compare ldl, vldl
Last Updated: - Updated example sentences
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