1
: either of two retroviruses (Lentivirus humimdef1 and L. humimdef2) that infect and destroy helper T cells of the immune system and that when left untreated cause AIDS

Note: HIV retroviruses are transmitted through contact with blood, semen, rectal and vaginal fluids, or breast milk and typically cause flu-like symptoms during the acute phase of infection, but often cause few or no symptoms during the chronic phase of infection when treated with antiretroviral drugs.

… the longer people are infected with HIV and the more immune-deficient they become, the more readily they seem to pass HIV to others.Robert R. Redfield et al.
Years of careful research have proven beyond doubt that the HIV virus causes AIDS, that antiretroviral drug treatment saves lives, and that the drug nevirapine is safe and effective in preventing the spread of HIV from mothers to their babies.Richard Marlink et al.

called also AIDS virus, human immunodeficiency virus

see also hiv-1, hiv-2
2
: the infection or disease caused by HIV
Early symptoms of HIV develop in 50 to 90 percent of people who are infected, usually beginning two to four weeks after exposure. … Because the signs and symptoms of … HIV may be similar to other common illnesses, such as mononucleosis, most people do not initially realize that they have HIV.Paul E. Sax

Examples of HIV in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Alston and Meeks formed the First Ladies Health Initiative in 2008 as a response to the impact of HIV and AIDS in Black communities. Bob Goldsborough, Chicago Tribune, 9 Apr. 2026 Gilead has so tightly limited access to the drug that millions of people at risk from HIV might not get it, according to Public Citizen. Business Columnist, Los Angeles Times, 9 Apr. 2026 The program offers federal funding for reproductive health services provided to low-income and uninsured patients, including birth control, cancer screenings, wellness exams and HIV testing. Aria Bendix, NBC news, 9 Apr. 2026 The pill, dubbed MK 8527, is currently undergoing a pair of late-stage clinical trials that are expected to determine whether the medicine can lower HIV transmission when given to people at high risk of infection. Ed Silverman, STAT, 7 Apr. 2026 See All Example Sentences for HIV

Word History

First Known Use

1986, in the meaning defined at sense 1

Time Traveler
The first known use of HIV was in 1986

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Cite this Entry

“HIV.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/HIV. Accessed 12 Apr. 2026.

Kids Definition

: any of a group of viruses that infect and destroy helper T cells causing the marked reduction in their numbers that is diagnostic of AIDS

Medical Definition

1
: either of two retroviruses (Lentivirus humimdef1 and L. humimdef2) that infect and destroy helper T cells of the immune system and that when left untreated cause AIDS

Note: HIV retroviruses are transmitted through contact with blood, semen, rectal and vaginal fluids, or breast milk and typically cause flu-like symptoms during the acute phase of infection, but often cause few or no symptoms during the chronic phase of infection when treated with antiretroviral drugs.

called also AIDS virus, human immunodeficiency virus

see also hiv-1, hiv-2
2
: the infection or disease caused by HIV
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