T cell

noun

: any of several lymphocytes (such as a helper T cell) that differentiate in the thymus, possess highly specific cell-surface antigen receptors, and include some that control the initiation or suppression of cell-mediated and humoral immunity (as by the regulation of T and B cell maturation and proliferation) and others that lyse antigen-bearing cells : t lymphocyte
The immature lymphoid cell, in turn, can be processed into a B cell, which makes infection-fighting antibodies, or a T cell, which recognizes foreign tissue and virally infected cells and directs the activities of the rest of the immune system.Gina Kolata
T cells recognize antigen only in association with cell surface molecules encoded by the major histocompatibility complexMiranda Robertson
see helper t cell, killer t cell compare b cell

Examples of T cell in a Sentence

Recent Examples on the Web
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But those preclinical studies uncovered how T cells, specialized white blood cells that are programmed to recognize and exterminate threats like cancer, are more active in the morning. Brenda Goodman, CNN Money, 6 Feb. 2026 Once fully accredited, Dell Children's will be able to do allogeneic transplants, which uses donor stem cells, as well as gene therapies and CAR T cell therapies. Nicole Villalpando, Austin American Statesman, 5 Feb. 2026 These parallels suggest that heart failure induces T cells to behave similarly to those in autoimmune disease rather than those that heal injuries. Shyam Bansal, The Conversation, 5 Feb. 2026 Because the brain has ordered the macrophages to create an immunosuppressive shield, the T cells lose their energy, stop multiplying and fail to recognize the cancer as a threat. Jacek Krywko, Scientific American, 4 Feb. 2026 See All Example Sentences for T cell

Word History

Etymology

thymus-derived cell

First Known Use

1970, in the meaning defined above

Time Traveler
The first known use of T cell was in 1970

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Cite this Entry

“T cell.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/T%20cell. Accessed 14 Feb. 2026.

Kids Definition

T cell

noun
: any of the lymphocytes (as a helper T cell) that usually mature in the thymus and take an active part in immune responses compare b cell

Medical Definition

T cell

noun
: any of several lymphocytes (as a helper T cell) that differentiate in the thymus, possess highly specific cell-surface antigen receptors, and include some that control the initiation or suppression of cell-mediated and humoral immunity (as by the regulation of T and B cell maturation and proliferation) and others that lyse antigen-bearing cells

called also T lymphocyte

see cytotoxic t cell, helper t cell, suppressor t cell, t4 cell

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