antagonize

verb

an·​tag·​o·​nize an-ˈta-gə-ˌnīz How to pronounce antagonize (audio)
antagonized; antagonizing
Synonyms of antagonizenext

transitive verb

1
: to incur or provoke the hostility of
His criticism antagonized his friends.
2
: to act in opposition to : counteract
The drug is antagonized by methylxanthines, such as caffeine and theophylline …Scientific American Medicine

Examples of antagonize in a Sentence

He didn't mean to antagonize you. Her comments antagonized many people.
Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
People from Maldonado’s group began antagonizing Jaquez’s group about not fully paying for their beer, according to the affidavit. Elissa Jorgensen, Dallas Morning News, 10 Feb. 2026 McPhatter berated the man and threw him against a patrol car twice, and when the man antagonized McPhatter from the back seat of his police cruiser, the cop reached back and grabbed the glasses off his face, prosecutors allege. John Annese, New York Daily News, 10 Feb. 2026 During the hearing, Republicans on the committee questioned agency leaders about the role of protestors antagonizing and threatening agents, as well as the rhetoric and decision-making of local leaders. Eric Henderson, CBS News, 10 Feb. 2026 Whether to avoid antagonizing potential donors or boxing themselves in as too far to the political left, some candidates, including Katie Porter and Eric Swalwell have largely avoided taking a hard and fast stance to this point. Douglas Schoen, Oc Register, 15 Jan. 2026 See All Example Sentences for antagonize

Word History

Etymology

Greek antagōnizesthai, from anti- + agōnizesthai to struggle, from agōn contest — more at agony

First Known Use

circa 1742, in the meaning defined at sense 2

Time Traveler
The first known use of antagonize was circa 1742

Browse Nearby Words

Cite this Entry

“Antagonize.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/antagonize. Accessed 14 Feb. 2026.

Kids Definition

antagonize

verb
an·​tag·​o·​nize an-ˈtag-ə-ˌnīz How to pronounce antagonize (audio)
antagonized; antagonizing
: to stir up dislike or anger in

Medical Definition

antagonize

transitive verb
an·​tag·​o·​nize
variants also British antagonise
antagonized also British antagonised; antagonizing also British antagonising
: to act in antagonism to : counteract
these effects are antagonized by atropineErnest Bueding & Harry Most

More from Merriam-Webster on antagonize

Last Updated: - Updated example sentences
Love words? Need even more definitions?

Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free!

More from Merriam-Webster