antagonize

verb

an·​tag·​o·​nize an-ˈta-gə-ˌnīz How to pronounce antagonize (audio)
antagonized; antagonizing

transitive verb

1
: to incur or provoke the hostility of
His criticism antagonized his friends.
2
: to act in opposition to : counteract
The drug is antagonized by methylxanthines, such as caffeine and theophylline …Scientific American Medicine

Examples of antagonize in a Sentence

He didn't mean to antagonize you. Her comments antagonized many people.
Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
His reign was not perfect, and his liberal creed antagonized enough conservative Catholics that a counter-movement has emerged in the U.S., complete with its own conferences, private schools and publications. Gustavo Arellano, Los Angeles Times, 23 Apr. 2025 The thinking is apparently that there is little to be gained by antagonizing a ruthless but also chaotic administration that just might flip the money spigot back on as quickly as it was shut off. Ars Staff, ArsTechnica, 17 Apr. 2025 Throughout their session, Jamie simultaneously antagonizes Briony, accusing her of trying to trick him and scaring her at several points by standing up and screaming directly in her face, and tries to win her over. Paula Mejía, The Atlantic, 16 Apr. 2025 And like much of the city’s Democratic establishment, the unions appear more interested in making amends than antagonizing a famously sharp-elbowed leader who could have influence over city contracts and other priorities. Nicholas Fandos, New York Times, 14 Apr. 2025 See All Example Sentences for antagonize

Word History

Etymology

Greek antagōnizesthai, from anti- + agōnizesthai to struggle, from agōn contest — more at agony

First Known Use

circa 1742, in the meaning defined at sense 2

Time Traveler
The first known use of antagonize was circa 1742

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Cite this Entry

“Antagonize.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/antagonize. Accessed 29 Apr. 2025.

Kids Definition

antagonize

verb
an·​tag·​o·​nize an-ˈtag-ə-ˌnīz How to pronounce antagonize (audio)
antagonized; antagonizing
: to stir up dislike or anger in

Medical Definition

antagonize

transitive verb
an·​tag·​o·​nize
variants also British antagonise
antagonized also British antagonised; antagonizing also British antagonising
: to act in antagonism to : counteract
these effects are antagonized by atropineErnest Bueding & Harry Most

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