antihistamine

noun

an·​ti·​his·​ta·​mine ˌan-tē-ˈhi-stə-ˌmēn How to pronounce antihistamine (audio)
-mən,
ˌan-tī-
: any of various compounds that counteract histamine in the body and that are used for treating allergic reactions (such as hay fever) and cold symptoms
antihistamine adjective
antihistaminic adjective or noun

Examples of antihistamine in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Another report suggested that this antihistamine reduced virus levels in nasal tissue. Katia Hetter, CNN Money, 12 Sep. 2025 This antihistamine is commonly used to treat allergy symptoms, including runny nose, watery eyes, and sneezing. Tom Gavin, EverydayHealth.com, 11 Sep. 2025 Each antihistamine tablet is formulated with 10 milligrams of cetirizine hydrochloride to help reduce hives and relieve itching due to hives. Adam Mills, MSNBC Newsweek, 10 Sep. 2025 Take an oral nonprescription antihistamine (Benadryl) or one with loratadine (Alavert, Claritin, others). Jalen Williams, Freep.com, 29 Aug. 2025 See All Example Sentences for antihistamine

Word History

First Known Use

1946, in the meaning defined above

Time Traveler
The first known use of antihistamine was in 1946

Browse Nearby Words

Cite this Entry

“Antihistamine.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/antihistamine. Accessed 21 Sep. 2025.

Kids Definition

antihistamine

noun
an·​ti·​his·​ta·​mine ˌant-i-ˈhis-tə-ˌmēn How to pronounce antihistamine (audio)
-mən,
ˌan-ˌtī-
: any of various drugs used for treating allergic reactions and cold symptoms

Medical Definition

antihistamine

1 of 2 adjective
an·​ti·​his·​ta·​mine ˌant-i-ˈhis-tə-ˌmēn, ˌan-ˌtī-, -mən How to pronounce antihistamine (audio)
: tending to block or counteract the physiological action of histamine
human blood lacks antihistamine activity

antihistamine

2 of 2 noun
: any of various compounds that oppose the actions of histamine and are used especially for treating allergic reactions (as hay fever), cold symptoms, and motion sickness

More from Merriam-Webster on antihistamine

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