atrophy

1 of 2

noun

plural atrophies
Synonyms of atrophy
1
: decrease in size or wasting away of a body part or tissue
atrophy of muscles
also : arrested development or loss of a part or organ incidental to the normal development or life of an animal or plant
2
: a wasting away or progressive decline
It was not a solitude of atrophy, of negation, but of perpetual flowering.Willa Cather
an atrophy of imagination
atrophied; atrophying; atrophies

transitive + intransitive

: to waste away (as from disease or disuse) : to undergo atrophy
Extended periods of weightlessness resulted in body fluids pooling in the upper torso, causing changes in how the heart pumped blood. In addition, muscles began to atrophy, bones lost calcium and mass …Warren E. Leary
Because of an incomplete spine, only one nerve serviced her legs, causing them to atrophy.Ada Brownell
Communion with nature strengthens both body and soul; isolation from nature causes both to atrophy.Mark Purcell
also : to cause (something) to waste away or undergo atrophy
Disuse atrophied the patient's arm.
When reform becomes too theological, it atrophies some forces even while it galvanizes others. John C. Culver
see also atrophied

Did you know?

What Can atrophy?

From its literal Greek roots, atrophy would mean basically "lack of nourishment". Although the English word doesn't usually imply any lack of food, it always refers to a wasting away. Those who have been bedridden for a period of time will notice that their muscles have atrophied. And muscular atrophy is a frequent result of such diseases as cancer and AIDS. We also use atrophy in a much more general sense. After being out of work a few years, you may find your work skills have atrophied; someone who's been living an isolated life may discover the same thing about his or her social skills; and a democracy can atrophy when its citizens cease to pay attention to how they're being governed.

Examples of atrophy in a Sentence

Noun The doctor is concerned about possible atrophy of the shoulder muscles.
Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Noun
But practicing and remembering how to use an analog clock may be another story—in other words, the skill may atrophy over time if it's not used. Jillian Pretzel, Parents, 30 June 2026 Nola Timmins was diagnosed with optic nerve atrophy and declared legally blind at 5 years old. Toria Sheffield, PEOPLE, 1 June 2026
Verb
Their defense industry and defense forces have atrophied. Efrat Lachter, FOXNews.com, 9 May 2026 Spending more than six months in space comes with other potential health risks, including the weakening and loss of bone and atrophying muscles. Jacopo Prisco, CNN Money, 26 May 2026 See All Example Sentences for atrophy

Word History

Etymology

Noun

Late Latin atrophia, from Greek, from atrophos ill fed, from a- + trephein to nourish

First Known Use

Noun

1601, in the meaning defined at sense 1

Verb

1863, in the meaning defined above

Time Traveler
The first known use of atrophy was in 1601

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Cite this Entry

“Atrophy.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/atrophy. Accessed 7 Jul. 2026.

Kids Definition

atrophy

1 of 2 noun
at·​ro·​phy
ˈa-trə-fē
plural atrophies
: decrease in size or wasting away of a body part or tissue

atrophy

2 of 2 verb
atrophied; atrophying
: to undergo atrophy

Medical Definition

atrophy

1 of 2 noun
plural atrophies
: decrease in size or wasting away of a body part or tissue
also : arrested development or loss of a part or organ incidental to the normal development or life of an animal or plant
atrophied; atrophying

intransitive verb

: to undergo atrophy
the inactive muscles atrophied

transitive verb

: to cause to undergo atrophy
disuse atrophied the arm

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