autoimmune

adjective

au·​to·​im·​mune ˌȯ-tō-im-ˈyün How to pronounce autoimmune (audio)
: of, relating to, or caused by autoantibodies or T cells that attack molecules, cells, or tissues of the organism producing them
autoimmune diseases
autoimmunity noun
autoimmunization noun

Did you know?

Any healthy body produces a variety of antibodies, proteins in the blood whose job is to protect the body from unwanted bacteria, viruses, and cancer cells. The cells and organs that deal with such infections make up the immune system. In some people and animals, for various reasons, the antibodies become overactive and turn on the body's healthy tissues as well; the result is an autoimmune disease—an immune response directed against one's own self. More than eighty autoimmune diseases have been identified, the best-known being type 1 diabetes, multiple sclerosis, lupus, and rheumatoid arthritis.

Examples of autoimmune in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
The aberrant action of our mosaic immune system attacking healthy cells is the basis of autoimmune disease. Jerome Groopman, New Yorker, 6 Apr. 2026 In December 2021, a year and a half after first noticing rashes and extreme exhaustion, then-20-year-old Broyden was diagnosed with dermatomyositis, a very rare autoimmune disease that causes severe reactions to sunlight. Nicki Cox, PEOPLE, 4 Apr. 2026 Hair loss can be caused by genetics, hormones, age, or underlying medical conditions (like some autoimmune diseases). Nicole Hernandez, USA Today, 3 Apr. 2026 Biegler's positive outlook comes from the company's portfolio of drugs to treat cancer and autoimmune diseases. Davis Giangiulio, CNBC, 1 Apr. 2026 See All Example Sentences for autoimmune

Word History

Etymology

auto- + immune, after autoimmunity, borrowed from French auto-immunité

First Known Use

1952, in the meaning defined above

Time Traveler
The first known use of autoimmune was in 1952

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Cite this Entry

“Autoimmune.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/autoimmune. Accessed 8 Apr. 2026.

Kids Definition

autoimmune

adjective
au·​to·​im·​mune ˌȯt-ō-im-ˈyün How to pronounce autoimmune (audio)
: relating to or caused by an abnormal condition in which an organism's immune system attacks and destroys parts of its own cells or tissues
multiple sclerosis is an autoimmune disease

Medical Definition

autoimmune

adjective
au·​to·​im·​mune -im-ˈyün How to pronounce autoimmune (audio)
: of, relating to, or caused by antibodies or T cells that attack molecules, cells, or tissues of the organism producing them
autoimmune diseases
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