buprenorphine

noun

bu·​pre·​nor·​phine ˌbyü-prə-ˈnȯr-ˌfēn How to pronounce buprenorphine (audio)
-fən
: a semisynthetic narcotic analgesic that is administered in the form of its hydrochloride C29H41NO4·HCl to control moderate to severe pain and treat opioid dependence

Note: Buprenorphine is administered by injection to control pain, is used in the form of a transdermal skin patch to control pain or treat opioid dependence, and is used in combination with naloxone in the form of a dissolvable tablet placed under the tongue or film placed inside the cheek to treat opioid dependence.

Examples of buprenorphine in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
The county has expanded the number of monthly buprenorphine injections and daily Suboxone strips dispensed to patients in custody in recent years, but routine budget restrictions continue to precipitate delays in treatment, according to Correctional Health Services. Gavin J. Quinton, Los Angeles Times, 19 June 2026 Still, methadone and buprenorphine — and a third medication, naltrexone — remain the only three drugs approved by the Food and Drug Administration specifically to treat opioid addiction. Lev Facher, STAT, 10 June 2026 An autopsy report revealed that the actor's death resulted from the acute effects of ketamine, with contributing factors including drowning, coronary artery disease, and the effects of buprenorphine, a prescription medication used to treat opioid use disorder. Emlyn Travis, Entertainment Weekly, 28 May 2026 Contributing factors include drowning, coronary artery disease and the effects of buprenorphine, which is used to treat opioid use disorder, the medical examiner said. City News Service, Daily News, 27 May 2026 See All Example Sentences for buprenorphine

Word History

First Known Use

1974, in the meaning defined above

Time Traveler
The first known use of buprenorphine was in 1974

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Cite this Entry

“Buprenorphine.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/buprenorphine. Accessed 20 Jun. 2026.

Medical Definition

buprenorphine

noun
bu·​pre·​nor·​phine ˌbyü-prə-ˈnȯr-ˌfēn, -fən How to pronounce buprenorphine (audio)
: a semisynthetic narcotic analgesic that is derived from thebaine and is administered in the form of its hydrochloride C29H41NO4·HCl to control moderate to severe pain and treat opioid dependence

Note: Buprenorphine is administered by injection to control pain, is used in the form of a transdermal skin patch to control pain or treat opioid dependence, and is used in combination with naloxone in the form of a dissolvable tablet placed under the tongue or film placed inside the cheek to treat opioid dependence. Trademarks for preparations containing buprenorphine include Bunavail, Buprenex, Butrans, Subutex, Suboxone, and Zubsolv.

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