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clozapine
noun
clo·za·pine
ˈklō-zə-ˌpēn
: an antipsychotic drug C18H19ClN4 used in the treatment of schizophrenia
Examples of clozapine in a Sentence
Recent Examples on the Web
At least one, Ryan Dunleavy of Brentwood, Tennessee, died from a deadly cocktail of fentanyl, MDMA (ecstasy) and clozapine.
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Kirsten Fiscus, The Tennessean, 14 June 2024
Medication side effects: Nonsteroidal anti-inflammatory drugs (NSAIDs) like Motrin (ibuprofen), serotonin receptor agonists like Clozaril (clozapine), and anticancer medications can all affect GI health.
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Mark Gurarie, Health, 2 Nov. 2024
Currently, the drug clozapine is the only option for treatment-resistant schizophrenia.
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Claire Bugos, Verywell Health, 30 Sep. 2024
The center is also participating in the clozapine study.
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Angela Roberts, Baltimore Sun, 1 July 2024
Other countries have been more discerning about clozapine’s public health calculus, resulting in less-stringent monitoring regulations and more widespread clozapine prescribing.
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Brian Barnett, STAT, 9 May 2022
To prevent and rapidly address cases of agranulocytosis, the FDA requires clozapine’s manufacturers to jointly administer the clozapine REMS program.
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Brian Barnett, STAT, 9 May 2022
Frustratingly, the antipsychotic that works best against schizophrenia’s symptoms—clozapine, which emerged in the late 1980s—can have the nastiest unwanted effects, including weight gain, diabetes, and excessive sleepiness.
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WIRED, 10 Feb. 2023
For them, clozapine is the gold standard treatment.
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Brian Barnett, STAT, 9 May 2022
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Word History
Etymology
International Scientific Vocabulary chlor- + -zapine, alteration of -azepine (as in benzodiazepine)
First Known Use
1970, in the meaning defined above
Dictionary Entries Near clozapine
Cite this Entry
“Clozapine.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/clozapine. Accessed 11 Feb. 2025.
Medical Definition
clozapine
noun
clo·za·pine
ˈklō-zə-ˌpēn
: an antipsychotic drug C18H19ClN4 with serious side effects (as seizures and agranulocytosis) that is used in the management of schizophrenia
Note: Clozapine is marketed under the trademark Clozaril.
More from Merriam-Webster on clozapine
Britannica.com: Encyclopedia article about clozapine
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