fentanyl

noun

fen·​ta·​nyl ˈfen-tə-ˌnil How to pronounce fentanyl (audio)
: a synthetic opioid narcotic analgesic C22H28N2O with pharmacological action similar to morphine that is administered transdermally as a skin patch and in the form of its citrate C22H28N2O·C6H8O7 is administered orally or parenterally (as by intravenous or epidural injection)

Examples of fentanyl in a Sentence

Recent Examples on the Web
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Both were federally charged with conspiracy to possess with intent to distribute heroin and fentanyl. Robert McGreevy, FOXNews.com, 3 July 2026 The suit did not specify what drug was involved, but said responding officers and paramedics gave the teen who sued multiple doses of Narcan, which is used to reverse overdoses caused by opioids such as fentanyl. James Queally, Los Angeles Times, 30 June 2026 Data from the Maryland Department of Health shows there were 20 overdose deaths between June 2025 and May 2026, including 13 fatal opioid overdoses and 12 overdose deaths involving fentanyl. Jt Moodee Lockman, CBS News, 30 June 2026 Lujan Grisham's remarks came a week after AP reported that DEA agents repeatedly monitored — but did not seize — shipments of fentanyl as part of an effort to build bigger criminal cases between 2023 and 2025. ABC News, 29 June 2026 See All Example Sentences for fentanyl

Word History

Etymology

probably alteration of phenethyl, a monovalent radical derived from ethylbenzine, from phen- + ethyl

First Known Use

1964, in the meaning defined above

Time Traveler
The first known use of fentanyl was in 1964

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Cite this Entry

“Fentanyl.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/fentanyl. Accessed 5 Jul. 2026.

Medical Definition

fentanyl

noun
fen·​ta·​nyl ˈfent-ᵊn-ˌil How to pronounce fentanyl (audio)
: a synthetic opioid narcotic analgesic C22H28N2O with pharmacological action similar to morphine that is administered transdermally as a skin patch and in the form of its citrate C22H28N2O·C6H8O7 is administered orally or parenterally

Note: Fentanyl is marketed under the trademark Actiq.

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