: relating to, being, or causing physiological changes in the body (such as an increase in heart rate or dilation of bronchi) in response to stress
epinephrine is a fight-or-flight hormone
a fight-or-flight reaction

Examples of fight-or-flight in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
And though stress is ever-present, an acute stressor that activates the fight-or-flight response, brought on by an argument or difficult situation, could exacerbate the situation, creating a perfect storm. Allison Aubrey, NPR, 17 Dec. 2025 The narrow Tuscan roads, steep curves, and zippy Italian drivers triggered a full fight-or-flight response. Hannah Howard, Travel + Leisure, 22 Nov. 2025 Your skin prickles, adrenaline spikes — and that primal fight-or-flight instinct kicks in. Sarah Hutter, CNN Money, 30 Oct. 2025 Over time, our nervous systems stay locked in fight-or-flight. Marc Brackett, Time, 28 Oct. 2025 See All Example Sentences for fight-or-flight

Word History

First Known Use

1973, in the meaning defined above

Time Traveler
The first known use of fight-or-flight was in 1973

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Cite this Entry

“Fight-or-flight.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/fight-or-flight. Accessed 1 Jan. 2026.

Medical Definition

fight-or-flight

adjective
ˌfī-tər-ˈflīt
: relating to, being, or causing physiological changes in the body (such as an increase in heart rate or dilation of bronchi) in response to stress
the fight-or-flight response
Last Updated: - Updated example sentences
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