genome

noun

ge·​nome ˈjē-ˌnōm How to pronounce genome (audio)
: one haploid set of chromosomes with the genes they contain
broadly : the genetic material of an organism compare proteome

Examples of genome in a Sentence

Recent Examples on the Web
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Its 90,000-base-pair genome enables the synthetic cell to produce proteins, replicate its DNA, feed, grow and divide into daughter cells. Greg Wehner, FOXNews.com, 3 July 2026 As noted above, though, that genome was only distributed into the next generation of cells at random, and pieces of it were progressively lost over each generation. ArsTechnica, 2 July 2026 Their tiny synthetic genome did not encode any metabolic genes, which would let the cell process food and energy, or many of the complex molecules a cell needs. Yasemin Saplakoglu, Quanta Magazine, 1 July 2026 Colossal says the partnership will integrate whole-genome sequence data into federal recovery plans and build a free genomic data platform that any researcher, wildlife manager or conservation organization worldwide can use. Mateo Rosiles, USA Today, 27 June 2026 See All Example Sentences for genome

Word History

Etymology

German Genom, from Gen gene + -om (as in Chromosom chromosome)

First Known Use

1926, in the meaning defined above

Time Traveler
The first known use of genome was in 1926

Browse Nearby Words

Cite this Entry

“Genome.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/genome. Accessed 5 Jul. 2026.

Medical Definition

genome

noun
ge·​nome ˈjē-ˌnōm How to pronounce genome (audio)
: one haploid set of chromosomes with the genes they contain
broadly : the genetic material of an organism
The idea behind sequencing an organism's genome—decoding, letter by letter, the message contained in every last one of its genes—is that it would tell us a lot about how the organism works. Lori Oliwenstein, Discover

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