: one haploid set of chromosomes with the genes they contain
broadly
: the genetic material of an organism compare proteome
Examples of genome in a Sentence
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When comparing the genome sequencing to other individuals within the two species, the researchers determined that the nuclear DNA was about a 50/50 split of the blue and green jay -- with the green jay as the likely mother, Stokes said.
—
Julia Jacobo, ABC News, 22 Sep. 2025
The researchers used deep sequencing, which is a way of reading DNA very precisely, to identify the exact places where HIV’s DNA landed inside the host genome.
—New Atlas, 20 Sep. 2025
This puzzle was resolved by scientists who sequenced the genome of a 35,000-year-old wolf from Siberia’s Taimyr Peninsula.
—Scott Travers, Forbes.com, 19 Sep. 2025
Earlier in April this year, Colossal claimed to have brought dire wolves out of extinction using a novel iterative genome assembly method.
—Atharva Gosavi, Interesting Engineering, 18 Sep. 2025
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Julia Jacobo, ABC News, 22 Sep. 2025
The researchers used deep sequencing, which is a way of reading DNA very precisely, to identify the exact places where HIV’s DNA landed inside the host genome.
—New Atlas, 20 Sep. 2025
This puzzle was resolved by scientists who sequenced the genome of a 35,000-year-old wolf from Siberia’s Taimyr Peninsula.
—Scott Travers, Forbes.com, 19 Sep. 2025
Earlier in April this year, Colossal claimed to have brought dire wolves out of extinction using a novel iterative genome assembly method.
—Atharva Gosavi, Interesting Engineering, 18 Sep. 2025
See All Example Sentences for genome
Cite this Entry
“Genome.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/genome. Accessed 23 Sep. 2025.
Copy CitationMedical Definition
genome
noun
ge·nome
ˈjē-ˌnōm 
: one haploid set of chromosomes with the genes they contain
broadly
: the genetic material of an organism
The idea behind sequencing an organism's genome—decoding, letter by letter, the message contained in every last one of its genes—is that it would tell us a lot about how the organism works. —Lori Oliwenstein, Discover
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