genome

noun

ge·​nome ˈjē-ˌnōm How to pronounce genome (audio)
: one haploid set of chromosomes with the genes they contain
broadly : the genetic material of an organism compare proteome

Examples of genome in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Scientists are sequencing the genomes in brain regions that postmortem studies show are affected by CTE to understand which cells and genes are aberrant. Alice Park, Time, 31 July 2025 Colossal created the mice by modifying seven genes simultaneously and from information gathered from analysis of woolly, Columbian and steppe mammoth genomes that were up to 1.2 million years old. Karoline Leonard, Austin American Statesman, 30 July 2025 Was Ozzy Osbourne a pioneer in the field of genome sequencing? George Varga, San Diego Union-Tribune, 23 July 2025 The researchers note, however, that more individual genome sequences would be needed to fully understand variation in ancestry during this period of Egyptian history. Jack Knudson, Discover Magazine, 18 July 2025 See All Example Sentences for genome

Word History

Etymology

German Genom, from Gen gene + -om (as in Chromosom chromosome)

First Known Use

1926, in the meaning defined above

Time Traveler
The first known use of genome was in 1926

Browse Nearby Words

Cite this Entry

“Genome.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/genome. Accessed 6 Aug. 2025.

Medical Definition

genome

noun
ge·​nome ˈjē-ˌnōm How to pronounce genome (audio)
: one haploid set of chromosomes with the genes they contain
broadly : the genetic material of an organism
The idea behind sequencing an organism's genome—decoding, letter by letter, the message contained in every last one of its genes—is that it would tell us a lot about how the organism works. Lori Oliwenstein, Discover

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