: one haploid set of chromosomes with the genes they contain
broadly
: the genetic material of an organism compare proteome
Examples of genome in a Sentence
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There are more advanced methods, such as whole genome sequencing, that can detect some rare genetic mutations among twins, but researchers say these techniques are complex, expensive and not commonly used in legal cases.
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Melissa Rudy, FOXNews.com, 1 Apr. 2026
It was convened in 1975 to discuss recombinant DNA, a then-new kind of genome editing.
—Big Think, 31 Mar. 2026
Recently published in the journal Nature, the latest study into the birth of the canine, which might have spawned an immediate bond between dog and man, reconstructed whole genomes, 10,000 years old, and cross-evaluated them with modern-day canines.
—Maria Mocerino, Interesting Engineering, 30 Mar. 2026
Take FlyBase — an online database of the Drosophila melanogaster (otherwise known as the fruit fly) genome, which for more than 30 years has been an essential resource for researchers studying everything from cancer genes to neurodegeneration to the fundamental mechanisms of inheritance.
—Megan Molteni, STAT, 27 Mar. 2026
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Melissa Rudy, FOXNews.com, 1 Apr. 2026
It was convened in 1975 to discuss recombinant DNA, a then-new kind of genome editing.
—Big Think, 31 Mar. 2026
Recently published in the journal Nature, the latest study into the birth of the canine, which might have spawned an immediate bond between dog and man, reconstructed whole genomes, 10,000 years old, and cross-evaluated them with modern-day canines.
—Maria Mocerino, Interesting Engineering, 30 Mar. 2026
Take FlyBase — an online database of the Drosophila melanogaster (otherwise known as the fruit fly) genome, which for more than 30 years has been an essential resource for researchers studying everything from cancer genes to neurodegeneration to the fundamental mechanisms of inheritance.
—Megan Molteni, STAT, 27 Mar. 2026
See All Example Sentences for genome
Cite this Entry
“Genome.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/genome. Accessed 5 Apr. 2026.
Copy CitationMedical Definition
genome
noun
ge·nome
ˈjē-ˌnōm 
: one haploid set of chromosomes with the genes they contain
broadly
: the genetic material of an organism
The idea behind sequencing an organism's genome—decoding, letter by letter, the message contained in every last one of its genes—is that it would tell us a lot about how the organism works. —Lori Oliwenstein, Discover
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