1
: either of two retroviruses (Lentivirus humimdef1 and L. humimdef2) that infect and destroy helper T cells of the immune system and that when left untreated cause AIDS

Note: HIV retroviruses are transmitted through contact with blood, semen, rectal and vaginal fluids, or breast milk and typically cause flu-like symptoms during the acute phase of infection, but often cause few or no symptoms during the chronic phase of infection when treated with antiretroviral drugs.

… the longer people are infected with HIV and the more immune-deficient they become, the more readily they seem to pass HIV to others.Robert R. Redfield et al.
Years of careful research have proven beyond doubt that the HIV virus causes AIDS, that antiretroviral drug treatment saves lives, and that the drug nevirapine is safe and effective in preventing the spread of HIV from mothers to their babies.Richard Marlink et al.

called also AIDS virus, human immunodeficiency virus

see also hiv-1, hiv-2
2
: the infection or disease caused by HIV
Early symptoms of HIV develop in 50 to 90 percent of people who are infected, usually beginning two to four weeks after exposure. … Because the signs and symptoms of … HIV may be similar to other common illnesses, such as mononucleosis, most people do not initially realize that they have HIV.Paul E. Sax

Examples of HIV in a Sentence

Recent Examples on the Web
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Health officials have shut down a Center City Philadelphia dental clinic and are urging former patients to get tested after possible exposure to the diseases Hepatitis B, Hepatitis C and HIV. Joe Brandt, CBS News, 20 May 2026 Wright cites Nigeria's $200 million supplementary health budget and South Africa's decision to help cover gaps in AIDS and HIV treatment as two examples. Ari Daniel, NPR, 19 May 2026 More people suffering from HIV/AIDS were able to procure antiretroviral therapy. Carrie Brandon Elliot, Forbes.com, 18 May 2026 More than three-quarters of HIV patients tied to the Penobscot County outbreak received care within 30 days of diagnosis, according to Maine CDC figures. Eric MacK, FOXNews.com, 18 May 2026 See All Example Sentences for HIV

Word History

First Known Use

1986, in the meaning defined at sense 1

Time Traveler
The first known use of HIV was in 1986

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Cite this Entry

“HIV.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/HIV. Accessed 21 May. 2026.

Kids Definition

: any of a group of viruses that infect and destroy helper T cells causing the marked reduction in their numbers that is diagnostic of AIDS

Medical Definition

1
: either of two retroviruses (Lentivirus humimdef1 and L. humimdef2) that infect and destroy helper T cells of the immune system and that when left untreated cause AIDS

Note: HIV retroviruses are transmitted through contact with blood, semen, rectal and vaginal fluids, or breast milk and typically cause flu-like symptoms during the acute phase of infection, but often cause few or no symptoms during the chronic phase of infection when treated with antiretroviral drugs.

called also AIDS virus, human immunodeficiency virus

see also hiv-1, hiv-2
2
: the infection or disease caused by HIV
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