hydrocodone

noun

hy·​dro·​co·​done ˌhī-drō-ˈkō-ˌdōn How to pronounce hydrocodone (audio)
: a habit-forming compound that is derived from codeine and is administered in the form of its bitartrate C18H21NO3·C4H6O6 usually in combination with other drugs (as acetaminophen) as an analgesic or cough suppressant

Examples of hydrocodone in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Fentanyl is a synthetic opioid and is included in data related to hydrocodone, oxycodone, methadone, morphine and heroin-related deaths. Kyle Werner, Des Moines Register, 9 Feb. 2026 Opioid Pain Medications Opioid pain medications, such as oxycodone, morphine, or hydrocodone, can cause sleepiness and slow breathing. Sarah Jividen, Verywell Health, 17 Jan. 2026 Includes cocaine, hydrocodone, fentanyl, Adderall, methamphetamine, oxycodone, Dexedrine, Ritalin, hydromorphone, meperidine and methadone, and others. Jenna Prestininzi, Freep.com, 19 Dec. 2025 He was supposed to receive ibuprofen and hydrocodone every eight hours. Natalie Eilbert, jsonline.com, 12 Nov. 2025 See All Example Sentences for hydrocodone

Word History

First Known Use

1964, in the meaning defined above

Time Traveler
The first known use of hydrocodone was in 1964

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Cite this Entry

“Hydrocodone.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/hydrocodone. Accessed 15 Feb. 2026.

Medical Definition

hydrocodone

noun
hy·​dro·​co·​done ˌhī-drō-ˈkō-ˌdōn How to pronounce hydrocodone (audio)
: a habit-forming compound derived from codeine and administered in the form of its bitartrate C18H21NO3·C4H6O6 usually in combination with other drugs (as acetaminophen) as an analgesic or cough sedative

called also dihydrocodeinone

see hycodan, vicodin
Last Updated: - Updated example sentences
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