investigational

adjective

in·​ves·​ti·​ga·​tion·​al in-ˌve-stə-ˈgā-sh(ə-)nəl How to pronounce investigational (audio)
1
: of or relating to investigation
investigational activities
2
: relating to or being a drug or medical procedure that is not approved for general use but is under investigation in clinical trials regarding its safety and efficacy
an investigational new drug

Examples of investigational in a Sentence

Recent Examples on the Web
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Generation Bio plans to announce the target and indication of its lead T cell-selective LNP-siRNA program for autoimmune disease by mid-year 2025, with an investigational new drug (IND) application submission expected in the second half of 2026. Quartz Intelligence Newsroom, Quartz, 13 Mar. 2025 Most cases come after the health insurance company asserted the service was experimental, investigational, not medically necessary, a clinical trial, or a treatment for a rare disease. David Robinson, USA TODAY, 7 Feb. 2025 The traditional approach requires pharmaceutical companies to conduct extensive clinical trials involving hundreds or thousands of patients, randomized to either receive the investigational treatment or a placebo. Greg Licholai Md, Forbes.com, 5 May 2025 Schmid worries their absence could impact the implementation of a new investigational PrEP medication that, if approved, would only need to be administered twice a year. Joseph Choi, The Hill, 15 Apr. 2025 See All Example Sentences for investigational

Word History

First Known Use

1905, in the meaning defined at sense 1

Time Traveler
The first known use of investigational was in 1905

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Cite this Entry

“Investigational.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/investigational. Accessed 21 Jun. 2025.

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