irritation

noun

ir·​ri·​ta·​tion ˌir-ə-ˈtā-shən How to pronounce irritation (audio)
Synonyms of irritationnext
1
a
: the state of being irritated
b
: something that irritates
c
: the act of irritating
2
: a condition of irritability, soreness, roughness, or inflammation of a bodily part

Examples of irritation in a Sentence

Dad's general irritation at the incessant complaining coming from the back seat of the car.
Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Monitor for irritation—discontinue any product that stings, burns or worsens symptoms. Lauryn Higgins, Flow Space, 18 May 2026 The cream is marketed to help relieve eczema symptoms including itching, dryness, redness, cracking and irritation. Angelique Brenes, PEOPLE, 15 May 2026 In animal studies, the system reduced blood pressure levels while avoiding much of the irritation and tissue damage associated with traditional implants. Aamir Khollam, Interesting Engineering, 15 May 2026 According to a 2025 review in Frontiers in Neuroscience, sneezing begins when specialized sensory receptors inside the nasal lining detect irritation. Scott Travers, Forbes.com, 15 May 2026 See All Example Sentences for irritation

Word History

First Known Use

15th century, in the meaning defined at sense 1c

Time Traveler
The first known use of irritation was in the 15th century

Browse Nearby Words

Cite this Entry

“Irritation.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/irritation. Accessed 20 May. 2026.

Kids Definition

irritation

noun
ir·​ri·​ta·​tion ˌir-ə-ˈtā-shən How to pronounce irritation (audio)
1
: the act of irritating : the state of being irritated
2

Medical Definition

irritation

noun
ir·​ri·​ta·​tion ˌir-ə-ˈtā-shən How to pronounce irritation (audio)
1
a
: the act of irritating
b
: something that irritates
c
: the state of being irritated
2
: a condition of irritability, soreness, roughness, or inflammation of a bodily part

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