keratin

noun

ker·​a·​tin ˈker-ə-tən How to pronounce keratin (audio)
: any of various sulfur-containing, fibrous, acidic or basic proteins chiefly of epithelial cells and tissues that are relatively insoluble and resistant to degradation, form filaments which assemble into bundles to provide structural support, and are the primary component of hair, nails, horns, claws, hooves, quills, scales, feathers and the epidermal layer of skin

Note: In addition to its structural properties, keratin also plays a role in cell growth and proliferation, cellular transport of substances, and intercellular communication.

Rhino horn is not actually horn but densely compacted fibers of keratin, a protein found in hair and fingernails.Maryanne Vollers
Wool fibers are composed of keratin proteins bundled into microfibrils.A. Goho
compare keratinocyte
keratinous adjective

Examples of keratin in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Ingredient-wise, Flores notes that it’s packed with argan oil, three types of honey, royal jelly, propolis, silk, and hyaluronic acid, along with keratin, ceramides, and rose extract to strengthen and moisturize strands. Iman Balagam, Vogue, 27 Dec. 2025 The secret weapon in question is bioactive keratin ferment, which manages to match proteins native to human hair while delivering vital nutrients straight to each strand’s cortex. Stacia Datskovska, Footwear News, 27 Dec. 2025 It’s designed with a simple and effective formulation featuring key ingredients such as vitamin B5, green tea extract, and myristoyl pentapeptide-17, a peptide that enhances keratin production to encourage hair growth (and strength). Jessie Quinn, StyleCaster, 15 Dec. 2025 Unlike texture release or keratin treatments, this one doesn’t require putting heat on the hair and isn’t intended to change or manipulate one’s hair texture. Annie Blay-Tettey, Allure, 15 Dec. 2025 See All Example Sentences for keratin

Word History

Etymology

borrowed from German Keratin, from Greek kerat-, stem of kéras "horn" + German -in -in entry 1 — more at kerato-

Note: The term was introduced by the German physician and chemist Johann Franz Simon (1807-43) in Handbuch der angewandten medizinischen Chemie, 1. Theil, Medizinisch-analytische Chemie (Berlin, 1840), p. 49.

First Known Use

circa 1849, in the meaning defined above

Time Traveler
The first known use of keratin was circa 1849

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Cite this Entry

“Keratin.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/keratin. Accessed 1 Jan. 2026.

Kids Definition

keratin

noun
ker·​a·​tin ˈker-ət-ᵊn How to pronounce keratin (audio)
: a sulfur-containing protein that makes up hair and horny tissues (as nails)

Medical Definition

keratin

noun
ker·​a·​tin ˈker-ət-ən How to pronounce keratin (audio)
: any of various sulfur-containing fibrous proteins that form the chemical basis of horny epidermal tissues (as hair and nails) and are typically not digested by enzymes of the gastrointestinal tract see pseudokeratin

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