keratin

noun

ker·​a·​tin ˈker-ə-tən How to pronounce keratin (audio)
: any of various sulfur-containing, fibrous, acidic or basic proteins chiefly of epithelial cells and tissues that are relatively insoluble and resistant to degradation, form filaments which assemble into bundles to provide structural support, and are the primary component of hair, nails, horns, claws, hooves, quills, scales, feathers and the epidermal layer of skin

Note: In addition to its structural properties, keratin also plays a role in cell growth and proliferation, cellular transport of substances, and intercellular communication.

Rhino horn is not actually horn but densely compacted fibers of keratin, a protein found in hair and fingernails.Maryanne Vollers
Wool fibers are composed of keratin proteins bundled into microfibrils.A. Goho
compare keratinocyte
keratinous adjective

Examples of keratin in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Estrogen is also important in producing a protein called keratin that’s made in the nail bed. Jocelyn Solis-Moreira, Flow Space, 13 Feb. 2026 Rosemary oil—one of the key ingredients in the mask—is like hair-growth gold, but ceramides, jojoba, and keratin are also present in the strengthening and thickening formula. Kaitlin Clapinski, InStyle, 10 Feb. 2026 And because the fibers are hollow (unlike synthetic fibers) and the keratin in them isn’t compatible with odor-causing bacteria, this sweater is breathable and stays fresh in between its infrequent washings. Katie Jackson, Travel + Leisure, 5 Feb. 2026 With hydrolyzed silk and hydrolyzed keratin to strengthen and repair, the spray provides all-day hold while keeping hair touchable and soft. Conçetta Ciarlo, Vogue, 15 Jan. 2026 See All Example Sentences for keratin

Word History

Etymology

borrowed from German Keratin, from Greek kerat-, stem of kéras "horn" + German -in -in entry 1 — more at kerato-

Note: The term was introduced by the German physician and chemist Johann Franz Simon (1807-43) in Handbuch der angewandten medizinischen Chemie, 1. Theil, Medizinisch-analytische Chemie (Berlin, 1840), p. 49.

First Known Use

circa 1849, in the meaning defined above

Time Traveler
The first known use of keratin was circa 1849

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Cite this Entry

“Keratin.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/keratin. Accessed 15 Feb. 2026.

Kids Definition

keratin

noun
ker·​a·​tin ˈker-ət-ᵊn How to pronounce keratin (audio)
: a sulfur-containing protein that makes up hair and horny tissues (as nails)

Medical Definition

keratin

noun
ker·​a·​tin ˈker-ət-ən How to pronounce keratin (audio)
: any of various sulfur-containing fibrous proteins that form the chemical basis of horny epidermal tissues (as hair and nails) and are typically not digested by enzymes of the gastrointestinal tract see pseudokeratin

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