lesion

noun

le·​sion ˈlē-zhən How to pronounce lesion (audio)
Synonyms of lesionnext
1
2
: an abnormal change in structure of an organ or part due to injury or disease
especially : one that is circumscribed (see circumscribe sense 1) and well-defined
lesioned adjective

Examples of lesion in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
The result is usually the result of lesions in the brain involved in identifying unique facial figures. Scott Lafee, San Diego Union-Tribune, 23 Dec. 2025 But in June the FDA approved EMROSI, an oral medication that directly targets the lesions while being gentle enough for aging skin. Helen Carefoot, Flow Space, 23 Dec. 2025 One woman, Megan Bent, recounted the story of her father, who was in a rehab facility after surgery to remove a cancerous lesion from his brain. Dhruv Khullar, New Yorker, 19 Dec. 2025 Treatment for vocal cord lesions can include voice therapy, surgery and lifestyle changes such as quitting smoking, reducing stress and improving one's diet, according to Cleveland Clinic. Edward Segarra, USA Today, 19 Dec. 2025 See All Example Sentences for lesion

Word History

Etymology

Middle English, from Anglo-French, from Latin laesion-, laesio, from laedere to injure

First Known Use

15th century, in the meaning defined at sense 1

Time Traveler
The first known use of lesion was in the 15th century

Browse Nearby Words

Cite this Entry

“Lesion.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/lesion. Accessed 31 Dec. 2025.

Kids Definition

lesion

noun
le·​sion ˈlē-zhən How to pronounce lesion (audio)
: a change in the structure of a bodily organ or part due to injury or disease
especially : an injured or diseased spot or area clearly marked off from healthy tissue around it

Medical Definition

lesion

1 of 2 noun
le·​sion ˈlē-zhən How to pronounce lesion (audio)
: an abnormal change in structure of an organ or part due to injury or disease
especially : one that is circumscribed and well defined
lesioned adjective

lesion

2 of 2 transitive verb
: to produce lesions in (as an animal's brain)

Legal Definition

lesion

noun
le·​sion ˈlē-zhən How to pronounce lesion (audio)
in the civil law of Louisiana : loss from failure to receive a threshold amount or value (as one-half market value) for immovable property conveyed or transferred by a commutative contract (as a sale or exchange)

called also lesion beyond moiety

compare unjust enrichment
Etymology

Anglo-French, damage, injury, from Latin laesio, from laedere to injure

More from Merriam-Webster on lesion

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