lipophilic
adjective
li·po·phil·ic
ˌlī-pə-ˈfi-lik 
ˌli-
ˌli-
: having an affinity for lipids (such as fats)
a lipophilic metabolite
Examples of lipophilic in a Sentence
Recent Examples on the Web
But the peptides in the new vaccine, called lipophilic peptides, have something past treatments did not — a tail.
—
Kaitlin Sullivan,
NBC news,
11 Aug. 2025
Many drugs are poorly water-soluble and lipophilic (fat-loving), and both pose challenges to bioavailability.
—
Paul McClure 13,
New Atlas,
13 Feb. 2025
Yadav said that vitamins could be administered transdermally, but only if they were formulated as nanoparticles and encased in a lipophilic (fat-soluble) substance.
—
Rachel Murphy,
Verywell Health,
11 June 2024
Hydrophilic molecules love water, while lipophilic molecules love fat.
—
Caroline Delbert,
Popular Mechanics,
6 May 2023
The ingredient is a beta-hydroxy acid, and one that’s lipophilic.
—
Melanie Rud,
Peoplemag,
7 Apr. 2023
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Kaitlin Sullivan,
NBC news,
11 Aug. 2025
Many drugs are poorly water-soluble and lipophilic (fat-loving), and both pose challenges to bioavailability.
—
Paul McClure 13,
New Atlas,
13 Feb. 2025
Yadav said that vitamins could be administered transdermally, but only if they were formulated as nanoparticles and encased in a lipophilic (fat-soluble) substance.
—
Rachel Murphy,
Verywell Health,
11 June 2024
Hydrophilic molecules love water, while lipophilic molecules love fat.
—
Caroline Delbert,
Popular Mechanics,
6 May 2023
The ingredient is a beta-hydroxy acid, and one that’s lipophilic.
—
Melanie Rud,
Peoplemag,
7 Apr. 2023
Cite this Entry
“Lipophilic.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/lipophilic. Accessed 6 Jul. 2026.
Copy CitationMedical Definition
lipophilic
adjective
li·po·phil·ic
ˌlip-ə-ˈfil-ik
ˌlīp-
ˌlīp-
: having an affinity for lipids (as fats)
a lipophilic metabolite
compare hydrophilic, lyophilic, oleophilic
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