: a semisynthetic illicit organic compound C20H25N3O derived from ergot that induces extreme sensory distortions, altered perceptions of reality, and intense emotional states, that may also produce delusions or paranoia, and that may sometimes cause panic reactions in response to the effects experienced

called also lysergic acid diethylamide

Examples of LSD in a Sentence

Recent Examples on the Web
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Horrific ethical violations aside, the experience was an overall pleasant one, and by the end of that year, all of the Beatles had experimented with LSD. Jordan Runtagh, People.com, 26 Apr. 2025 However, when they were given a small amount of LSD, a psychedelic drug known for its mind-altering effects, their brain activity and social behaviors improved, reestablishing their connection with humans. Ross Rosenfeld, MSNBC Newsweek, 23 Apr. 2025 Psilocybin use in 2023 among adults was higher than estimates for cocaine, illicit opioid use, methamphetamine or LSD (lysergic acid diethylamide), the study found. Sandee Lamotte, CNN Money, 21 Apr. 2025 Scully worked on electronics and assisted in some light LSD tableting. John Semley, Rolling Stone, 19 Apr. 2025 See All Example Sentences for LSD

Word History

Etymology

borrowed from German, from Lysergsäure-Diäthylamid "lysergic acid diethylamide"

First Known Use

1950, in the meaning defined above

Time Traveler
The first known use of LSD was in 1950

Browse Nearby Words

Cite this Entry

“LSD.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/LSD. Accessed 30 Apr. 2025.

Kids Definition

: an illegal drug that causes abnormal sensations, extreme and changeable states of emotion, unnatural changes in the way time and space are experienced, and hallucinations and that may sometimes cause panic in response to the effects experienced

Medical Definition

: a semisynthetic illicit organic compound C20H25N3O derived from ergot that induces extreme sensory distortions, altered perceptions of reality, and intense emotional states, that may also produce delusions or paranoia, and that may sometimes cause panic reactions in response to the effects experienced

called also acid, lysergic acid diethylamide, lysergide

More from Merriam-Webster on LSD

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