: any of a breed of very large massive powerful smooth-coated dogs that are apricot, fawn, or brindle and are often used as guard dogs
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But just reaching the elite, champions-only show is a major accomplishment in dogdom, especially for first-timers such as Joseph Carrero and his Neapolitan mastiff, Dezi.—CBS News, 4 Feb. 2026 But just reaching the elite, champions-only show is a major accomplishment in dogdom, especially for first-timers such as Joseph Carrero and his Neapolitan mastiff, Dezi.—Jennifer Peltz, Chicago Tribune, 3 Feb. 2026 Breeds commonly seen in Milwaukee – such as pit bull mixes, cane corsos and mastiffs – can’t tolerate more than 15 minutes in freezing weather.—Quinn Clark, jsonline.com, 22 Jan. 2026 Jones, 1-year-old mastiff mix, #967270.—Linda McIntosh, San Diego Union-Tribune, 22 Dec. 2025 See All Example Sentences for mastiff
Word History
Etymology
Middle English mastif, from Medieval Latin mastivus, from Vulgar Latin *masuetivus, from Latin mansuetus tame — more at mansuetude