melanoma

noun

mel·​a·​no·​ma ˌme-lə-ˈnō-mə How to pronounce melanoma (audio)
plural melanomas also melanomata ˌme-lə-ˈnō-mə-tə How to pronounce melanoma (audio)
Synonyms of melanomanext
1
: a tumor containing dark pigment
2
: a highly malignant tumor that starts in melanocytes of normal skin or moles and metastasizes rapidly and widely

Examples of melanoma in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
But early skin cancer, including aggressive melanoma, could be missed with just a visual exam. Cindy Krischer Goodman, Miami Herald, 27 May 2026 Beyond melanoma detection The study used mouse models engineered with genetic mutations similar to human melanoma. Aamir Khollam, Interesting Engineering, 25 May 2026 Even more striking, dermatologists were more than 13 times as likely as primary care physicians to accurately diagnose melanoma using dermoscopic imaging. Cindy Krischer Goodman, Sun Sentinel, 23 May 2026 In April, the FDA rejected Replimune’s drug candidate for melanoma a second time after an initial rejection in July. Annika Kim Constantino,angelica Peebles, CNBC, 12 May 2026 See All Example Sentences for melanoma

Word History

Etymology

melan- (in melanosis, melanotic) + -oma

First Known Use

1838, in the meaning defined at sense 1

Time Traveler
The first known use of melanoma was in 1838

Browse Nearby Words

Cite this Entry

“Melanoma.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/melanoma. Accessed 29 May. 2026.

Kids Definition

melanoma

noun
mel·​a·​no·​ma ˌmel-ə-ˈnō-mə How to pronounce melanoma (audio)
plural melanomas also melanomata -mət-ə How to pronounce melanoma (audio)
: a usually malignant tumor containing dark pigment

Medical Definition

melanoma

noun
mel·​a·​no·​ma ˌmel-ə-ˈnō-mə How to pronounce melanoma (audio)
plural melanomas also melanomata -mət-ə How to pronounce melanoma (audio)
1
: a benign or malignant skin tumor containing dark pigment
2
: a tumor of high malignancy that starts in melanocytes of normal skin or moles and metastasizes rapidly and widely

called also malignant melanoma, melanocarcinoma, melanoepithelioma, melanosarcoma

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