melanoma

noun

mel·​a·​no·​ma ˌme-lə-ˈnō-mə How to pronounce melanoma (audio)
plural melanomas also melanomata ˌme-lə-ˈnō-mə-tə How to pronounce melanoma (audio)
Synonyms of melanomanext
1
: a tumor containing dark pigment
2
: a highly malignant tumor that starts in melanocytes of normal skin or moles and metastasizes rapidly and widely

Examples of melanoma in a Sentence

Recent Examples on the Web
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Potential adverse effects identified by the FDA in this 14-item list include heart toxicity, infections, pancreatitis, increased or decreased insulin sensitivity, serious immunoresponses, melanoma and death. Mary Walrath-Holdridge, USA Today, 1 Apr. 2026 Australians have a complicated relationship with the Sun, suffering the world’s highest melanoma rates even with a functioning ozone layer. Big Think, 31 Mar. 2026 Over the years, Vitale has had several diagnoses including melanoma and lymphoma, all while keeping his fans abreast of his health status. Michael Gallagher, MSNBC Newsweek, 31 Mar. 2026 Clinical trials are showing success against pancreatic cancer, melanoma, and rare genetic disorders that were previously untreatable. Jeff Coller, Fortune, 26 Mar. 2026 See All Example Sentences for melanoma

Word History

Etymology

melan- (in melanosis, melanotic) + -oma

First Known Use

1838, in the meaning defined at sense 1

Time Traveler
The first known use of melanoma was in 1838

Browse Nearby Words

Cite this Entry

“Melanoma.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/melanoma. Accessed 7 Apr. 2026.

Kids Definition

melanoma

noun
mel·​a·​no·​ma ˌmel-ə-ˈnō-mə How to pronounce melanoma (audio)
plural melanomas also melanomata -mət-ə How to pronounce melanoma (audio)
: a usually malignant tumor containing dark pigment

Medical Definition

melanoma

noun
mel·​a·​no·​ma ˌmel-ə-ˈnō-mə How to pronounce melanoma (audio)
plural melanomas also melanomata -mət-ə How to pronounce melanoma (audio)
1
: a benign or malignant skin tumor containing dark pigment
2
: a tumor of high malignancy that starts in melanocytes of normal skin or moles and metastasizes rapidly and widely

called also malignant melanoma, melanocarcinoma, melanoepithelioma, melanosarcoma

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