methamphetamine

noun

meth·​am·​phet·​amine ˌme-tham-ˈfe-tə-ˌmēn How to pronounce methamphetamine (audio)
-thəm-
-mən
: a synthetic or semisynthetic compound C10H15N that stimulates the central nervous system, is used medically in the form of its crystalline hydrochloride C10H15N·HCl especially to treat attention deficit hyperactivity disorder and obesity, and that is often abused illicitly for its stimulant properties
methamphetamine is a powerful addictive stimulant whose longtime consumers tend to suffer from paranoia, depression, hallucinations, and violent rages.William Finnegan

called also meth, methedrine, speed

compare crystal meth

Examples of methamphetamine in a Sentence

Recent Examples on the Web
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The sting resulted in the seizure of more than 100 cellphones, methamphetamines, synthetic cannabinoids, and other narcotics, officials said. Doug Myers, CBS News, 2 Apr. 2026 Two people were arrested after around 100 pounds of crystal methamphetamine were found during a traffic stop, according to a news release from the Jeffersontown Police Department. Caroline Neal, Louisville Courier Journal, 1 Apr. 2026 Most recently, on March 22, one of the family's dogs again became ill after eating an unknown substance in the front yard, and tested positive for both methamphetamine and MDMA, or ecstasy. Jeanine Santucci, USA Today, 31 Mar. 2026 Police in Broomfield, Colorado, opened an investigation after multiple hot dogs laced with methamphetamine were found in a family’s yard and sickened at least two dogs, according to a press release. Hollie Silverman, MSNBC Newsweek, 30 Mar. 2026 See All Example Sentences for methamphetamine

Word History

First Known Use

1949, in the meaning defined above

Time Traveler
The first known use of methamphetamine was in 1949

Browse Nearby Words

Cite this Entry

“Methamphetamine.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/methamphetamine. Accessed 5 Apr. 2026.

Kids Definition

methamphetamine

noun
meth·​am·​phet·​amine ˌmeth-am-ˈfet-ə-ˌmēn How to pronounce methamphetamine (audio)
: a drug derived from amphetamine that is often used illegally as a stimulant of the central nervous system

Medical Definition

methamphetamine

noun
meth·​am·​phet·​amine ˌmeth-am-ˈfet-ə-ˌmēn, ˌmeth-əm-, -mən How to pronounce methamphetamine (audio)
: an amine C10H15N that is used medically in the form of its crystalline hydrochloride C10H15N·HCl especially to treat attention deficit hyperactivity disorder and obesity and that is often abused illicitly as a stimulant

called also meth, methedrine, methylamphetamine, speed

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