methamphetamine

noun

meth·​am·​phet·​amine ˌme-tham-ˈfe-tə-ˌmēn How to pronounce methamphetamine (audio)
-thəm-
-mən
: a synthetic or semisynthetic compound C10H15N that stimulates the central nervous system, is used medically in the form of its crystalline hydrochloride C10H15N·HCl especially to treat attention deficit hyperactivity disorder and obesity, and that is often abused illicitly for its stimulant properties
methamphetamine is a powerful addictive stimulant whose longtime consumers tend to suffer from paranoia, depression, hallucinations, and violent rages.William Finnegan

called also meth, methedrine, speed

compare crystal meth

Examples of methamphetamine in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Kroth pleaded guilty in October 2023 to conspiracy to commit wire fraud and possession with intent to distribute methamphetamine. Brittny Mejia, Los Angeles Times, 5 Feb. 2026 The United Nations has said in recent years that organized crime groups trafficking cocaine and methamphetamine have expanded their presence in the Pacific. CBS News, 5 Feb. 2026 Drug dealers mix fentanyl, because of its potency and low cost, with other drugs including heroin, methamphetamine and cocaine, which increases the likelihood of a fatal dose, according to the DEA. Rosalio Ahumada, Sacbee.com, 4 Feb. 2026 Federal prosecutors say Katzin ran a ring of drug dealers who peddled fentanyl, methamphetamine and heroin to customers throughout the city and Sklar was one of her underlings. Roni Jacobson, New York Daily News, 3 Feb. 2026 See All Example Sentences for methamphetamine

Word History

First Known Use

1949, in the meaning defined above

Time Traveler
The first known use of methamphetamine was in 1949

Browse Nearby Words

Cite this Entry

“Methamphetamine.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/methamphetamine. Accessed 15 Feb. 2026.

Kids Definition

methamphetamine

noun
meth·​am·​phet·​amine ˌmeth-am-ˈfet-ə-ˌmēn How to pronounce methamphetamine (audio)
: a drug derived from amphetamine that is often used illegally as a stimulant of the central nervous system

Medical Definition

methamphetamine

noun
meth·​am·​phet·​amine ˌmeth-am-ˈfet-ə-ˌmēn, ˌmeth-əm-, -mən How to pronounce methamphetamine (audio)
: an amine C10H15N that is used medically in the form of its crystalline hydrochloride C10H15N·HCl especially to treat attention deficit hyperactivity disorder and obesity and that is often abused illicitly as a stimulant

called also meth, methedrine, methylamphetamine, speed

More from Merriam-Webster on methamphetamine

Last Updated: - Updated example sentences
Love words? Need even more definitions?

Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free!

More from Merriam-Webster