molecule

noun

mol·​e·​cule ˈmä-li-ˌkyül How to pronounce molecule (audio)
1
: the smallest particle of a substance that retains all the properties (see property sense 1a) of the substance and is composed of one or more atoms (see atom sense 1a)
a molecule of water
a molecule of oxygen
2
: a tiny bit : particle
a molecule of political honestyTime

Examples of molecule in a Sentence

There is not a molecule of evidence to support these charges. not a molecule of sense in that girl
Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
The life sciences sector is increasingly ambitious in its drug development activity, discovering and harnessing new molecules and devising more targeted therapies with implications for clinical trials and in-market safety monitoring. Aman Wasan, Forbes.com, 19 Sep. 2025 Scientists tested more than 300 combinations of growth factors, small molecules, and metabolites to develop the cells of Nicobar pigeons, the closest relative to the dodo. Reed Albergotti, semafor.com, 19 Sep. 2025 That protection could increase the odds that organic molecules still exist intact here. Stefanie Waldek, Space.com, 19 Sep. 2025 Diet sodas and other zero-calorie drinks are a mainstay of the modern diet, thanks to the development of artificial sweeteners whose molecules can't be metabolized by the human body. ArsTechnica, 18 Sep. 2025 See All Example Sentences for molecule

Word History

Etymology

French molécule, from New Latin molecula, diminutive of Latin moles mass

First Known Use

1701, in the meaning defined at sense 1

Time Traveler
The first known use of molecule was in 1701

Browse Nearby Words

Cite this Entry

“Molecule.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/molecule. Accessed 24 Sep. 2025.

Kids Definition

molecule

noun
mol·​e·​cule ˈmäl-i-ˌkyü(ə)l How to pronounce molecule (audio)
1
: the smallest particle of a substance having all the characteristics of the substance
a molecule of water
a molecule of oxygen
2
: a very small bit : particle

Medical Definition

molecule

noun
mol·​e·​cule ˈmäl-i-ˌkyü(ə)l How to pronounce molecule (audio)
: the smallest particle of a substance that retains all the properties of the substance and is composed of one or more atoms

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