naltrexone
noun
nal·trex·one
nal-ˈtrek-ˌsōn 
: a synthetic opiate antagonist C20H23NO4 administered in the form of its hydrochloride
Examples of naltrexone in a Sentence
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When people were also treated with a long-acting form of an opioid-blocking medication called naltrexone, relapse rates dropped across all settings — to 59% after short-term inpatient care, 46% after long-term inpatient care and 38% for those treated as outpatients.
—
Emma Fenske, The Conversation, 12 Feb. 2026
The prescription opioid pill, called naltrexone, was first approved by the FDA to treat opioid dependence in 1984.
—Melissa Rudy, FOXNews.com, 7 Jan. 2026
Opioid use disorder can be treated with buprenorphine, methadone, or naltrexone.
—Ciara McCarthy, Fort Worth Star-Telegram, 7 Oct. 2025
Everyone has the right to their own solution The truth is that there is no silver bullet — neither AA nor naltrexone nor anything else.
—Jonathan Hunt-Glassman, Fortune, 21 Sep. 2025
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Emma Fenske, The Conversation, 12 Feb. 2026
The prescription opioid pill, called naltrexone, was first approved by the FDA to treat opioid dependence in 1984.
—Melissa Rudy, FOXNews.com, 7 Jan. 2026
Opioid use disorder can be treated with buprenorphine, methadone, or naltrexone.
—Ciara McCarthy, Fort Worth Star-Telegram, 7 Oct. 2025
Everyone has the right to their own solution The truth is that there is no silver bullet — neither AA nor naltrexone nor anything else.
—Jonathan Hunt-Glassman, Fortune, 21 Sep. 2025
See All Example Sentences for naltrexone
Cite this Entry
“Naltrexone.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/naltrexone. Accessed 26 Feb. 2026.
Copy CitationMedical Definition
naltrexone
noun
nal·trex·one
nal-ˈtrek-ˌsōn
: a synthetic opiate antagonist administered especially in the form of its hydrochloride C20H23NO4·HCl to maintain a drug-free state in detoxified opiate-dependent patients or to maintain abstinence in alcohol-dependent patients
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