neuroactive

adjective

neu·​ro·​ac·​tive ˌnu̇r-ō-ˈak-tiv How to pronounce neuroactive (audio)
ˌnyu̇r-
: stimulating neural tissue

Examples of neuroactive in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Known as a neuroactive steroid, the zuranolone mimics a form of progesterone that the brain naturally produces and whose levels rise significantly during pregnancy. Manasee Wagh, Popular Mechanics, 22 Aug. 2023 On the whole, Alpert is encouraged by the many new options on the horizon for treating depression, including magnetic stimulation, neuroactive steroids, ketamine and psychedelic medicines like psilocybin and MDMA. Brianna Randall, Discover Magazine, 7 Apr. 2022 Allopregnanolone is a neuroactive steroid, structurally similar to progesterone, that acts on GABA receptors and is believed to improve symptoms of depression and anxiety by amplifying GABAergic signaling throughout the brain. Husseini Manji, Scientific American, 14 Sep. 2021

Word History

First Known Use

1961, in the meaning defined above

Time Traveler
The first known use of neuroactive was in 1961

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Cite this Entry

“Neuroactive.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/neuroactive. Accessed 5 Jul. 2026.

Medical Definition

neuroactive

adjective
neu·​ro·​ac·​tive ˌn(y)u̇r-ō-ˈak-tiv How to pronounce neuroactive (audio)
: stimulating neural tissue
injected a neuroactive substance into the blood
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