neurodegenerative

adjective

neu·​ro·​de·​gen·​er·​a·​tive ˌnu̇r-ō-di-ˈje-nə-rə-tiv How to pronounce neurodegenerative (audio)
-ˈjen-rə-;
-ˈje-nə-ˌrā-;
-dē-,
ˌnyu̇r-
: relating to or marked by degeneration of nervous tissue

Examples of neurodegenerative in a Sentence

Recent Examples on the Web
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Dane, 52, has spoken candidly about his journey with amyotrophic lateral sclerosis (ALS), a neurodegenerative disease that affects the motor neurons in the brain and spinal cord. Jessica Wang, Entertainment Weekly, 15 Sep. 2025 Dudley said further research needed could include seeing if the shift observed also occurs in other neurodegenerative or inflammatory conditions. Hannah Millington, MSNBC Newsweek, 12 Sep. 2025 My dad suffered from Creutzfeldt-Jakob Disease, another neurodegenerative illness. David Oliver, USA Today, 11 Sep. 2025 But in modern humans, HERV-K Env proteins show up on the surface of certain tumor cells and in patients with autoimmune and neurodegenerative diseases. Ashley MacKin Solomon, San Diego Union-Tribune, 9 Sep. 2025 See All Example Sentences for neurodegenerative

Word History

First Known Use

1907, in the meaning defined above

Time Traveler
The first known use of neurodegenerative was in 1907

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Cite this Entry

“Neurodegenerative.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/neurodegenerative. Accessed 18 Sep. 2025.

Medical Definition

neurodegenerative

adjective
neu·​ro·​de·​gen·​er·​a·​tive -di-ˈjen-ə-ˌrāt-iv, -di-ˈjen-(ə-)rət- How to pronounce neurodegenerative (audio)
: relating to or characterized by degeneration of nervous tissue
neurodegeneration noun
Last Updated: - Updated example sentences
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