off-label
adjective
off-la·bel
ˈȯf-ˌlā-bəl 
: of, relating to, or being a drug used to treat a condition for which it has not been officially approved
Examples of off-label in a Sentence
Recent Examples on the Web
The Justice Department has repeatedly argued that the information sought in the subpoenas is needed to investigate possible fraud or unlawful off-label promotion of drugs.
—
ABC News, 14 May 2026
For instance, the diabetes medication Metformin is not officially approved for PMOS, but is sometimes prescribed off-label.
—Abby Norman, Verywell Health, 14 May 2026
Ivermectin–benzimidazole, a combination of antiparasitic medications, was touted as an off-label cancer treatment during actor Mel Gibson’s January 2025 appearance.
—Melissa Rudy, FOXNews.com, 13 May 2026
Perry had been receiving ketamine treatments for depression — an increasingly common off-label use.
—Andrew Dalton, Chicago Tribune, 13 May 2026
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ABC News, 14 May 2026
For instance, the diabetes medication Metformin is not officially approved for PMOS, but is sometimes prescribed off-label.
—Abby Norman, Verywell Health, 14 May 2026
Ivermectin–benzimidazole, a combination of antiparasitic medications, was touted as an off-label cancer treatment during actor Mel Gibson’s January 2025 appearance.
—Melissa Rudy, FOXNews.com, 13 May 2026
Perry had been receiving ketamine treatments for depression — an increasingly common off-label use.
—Andrew Dalton, Chicago Tribune, 13 May 2026
See All Example Sentences for off-label
Cite this Entry
“Off-label.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/off-label. Accessed 21 May. 2026.
Copy CitationMedical Definition
off-label
adjective
off-la·bel
ˌȯf-ˌlā-bəl
: of, relating to, or being an approved drug legally prescribed or a medical device legally used by a physician for a purpose (as the treatment of children or of a certain disease or condition) for which it has not been specifically approved (as by the United States Food and Drug Administration)
the off-label use of oral contraceptives to treat dysmenorrhea
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