: any of a family (Picornaviridae) of small single-stranded RNA viruses that include the causative agents of hepatitis A, polio, foot-and-mouth disease, and hand, foot and mouth disease compare enterovirus, rhinovirus

Word History

Etymology

pico- + RNA + virus

First Known Use

1962, in the meaning defined above

Time Traveler
The first known use of picornavirus was in 1962

Browse Nearby Words

Cite this Entry

“Picornavirus.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/picornavirus. Accessed 7 Jul. 2026.

Medical Definition

picornavirus

noun
: any of the family Picornaviridae of single-stranded RNA viruses

More from Merriam-Webster on picornavirus

Love words? Need even more definitions?

Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free!