polynucleotide

noun

poly·​nu·​cle·​o·​tide ˌpä-lē-ˈnü-klē-ə-ˌtīd How to pronounce polynucleotide (audio)
-ˈnyü-
: a polymeric chain of nucleotides

Examples of polynucleotide in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
In the spring, polynucleotides — DNA derived from salmon or trout — took off, with experts using them in facial treatments to repair skin and boost hydration. — Jacqueline Kilikita, Refinery29, 24 Dec. 2025 As Allure previously reported, studies have shown that polynucleotides can be beneficial for tissue regeneration and to stimulate collagen production. — Kara Nesvig, Allure, 16 Aug. 2025 One study conducted on wound healing in mice showed that administering polynucleotides expedited healing and collagen density. — Maddie Connors, Los Angeles Times, 14 May 2025 Essentially, polynucleotides are fragments of DNA that are typically derived from salmon sperm that can enhance the body's natural renewal process. — Perrie Samotin, Glamour, 3 May 2025 The polynucleotides aren't sperm in the literal sense, Kopelman explained. — Kathleen Ferraro, Verywell Health, 31 Mar. 2025

Word History

Etymology

International Scientific Vocabulary

First Known Use

1911, in the meaning defined above

Time Traveler
The first known use of polynucleotide was in 1911

Rhymes for polynucleotide

See All Rhymes for polynucleotide

Browse Nearby Words

polynuclear aromatic hydrocarbon
polynucleotide
polynya
See all Nearby Words

Cite this Entry

“Polynucleotide.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/polynucleotide. Accessed 1 Aug. 2026.

Copy Citation

Medical Definition

polynucleotide

noun
poly·​nu·​cle·​o·​tide -ˈn(y)ü-klē-ə-ˌtīd How to pronounce polynucleotide (audio)
: a polymeric chain of mononucleotides
Last Updated: - Updated example sentences
Love words? Need even more definitions?

Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free!

More from Merriam-Webster

Word of the Day

Listen to the pronunciation of spindrift

See Definitions and Examples »

Popular in Grammar & Usage

See More

7 Pairs of Commonly Confused Words

Merriam-Webster’s Great Big List of Words You Love to Hate

Is it 'nerve-racking' or 'nerve-wracking'?

Why does English have so many silent letters?

Your vs. You're: How to Use Them Correctly
See More

Popular in Wordplay

See More

Dutch Treat and French Leave: Eight Place-Based Compounds

14 Phobias You Probably Haven't Heard Of

The Longest Long Words List

The Words of the Week - Jul. 31

Even More Bird Names that Sound Like Insults (and Sometimes Are)
See More

Popular

See More

7 Pairs of Commonly Confused Words

Dutch Treat and French Leave: Eight Place-Based Compounds

14 Phobias You Probably Haven't Heard Of
See More

Games & Quizzes

See All
Play Quordle: Guess all four words in a limited number of tries. Each of your guesses must be a real 5-letter word.
Quordle Can you solve 4 words at once?
Play Blossom: Solve today's spelling word game by finding as many words as you can using just 7 letters. Longer words score more points.
Blossom Pick the best words!
Play Missing Letter: a crossword with a twist. Each of the 25 puzzle words start with a different letter of the alphabet. Which letter is missing?
The Missing Letter A daily crossword with a twist
asap street sign
Figure Out These Acronyms ASAP You don't have to be a NASA engineer to get these...
See All