psilocybin

noun

psi·​lo·​cy·​bin ˌsī-lə-ˈsī-bən How to pronounce psilocybin (audio)
: a hallucinogenic indole C12H17N2O4P obtained from a fungus (such as Psilocybe mexicana or P. cubensis synonym Stropharia cubensis)

Examples of psilocybin in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
People who use psilocybin recreationally may become confused and jump off a building, David Yaden, a researcher at the Center for Psychedelic and Consciousness Research at Johns Hopkins University, told me. Ross Andersen, The Atlantic, 12 June 2026 As the patient may have experienced natural fluctuations in her medical condition, the study could not establish that psilocybin directly caused the woman’s improvements. Melissa Rudy, FOXNews.com, 9 June 2026 The analog girl in a digital world took the stage on Sunday evening to close out the festival wearing what looked like a mushroom cap on her head, accented by a frilly, droopy outfit that looked like it was designed by psilocybin. Steven J. Horowitz, Variety, 1 June 2026 While drugs like psilocybin and ibogaine — a psychoactive compound derived from a West African shrub that some advocates believe may help treat addiction and traumatic brain injuries — are considered classic psychedelics, MDMA is technically classified as an empathogen. Brandon Gomez, CNBC, 31 May 2026 See All Example Sentences for psilocybin

Word History

Etymology

New Latin Psilocybe, fungus genus + -in entry 1

First Known Use

1958, in the meaning defined above

Time Traveler
The first known use of psilocybin was in 1958

Browse Nearby Words

Cite this Entry

“Psilocybin.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/psilocybin. Accessed 20 Jun. 2026.

Kids Definition

psilocybin

noun
psi·​lo·​cy·​bin ˌsī-lə-ˈsī-bən How to pronounce psilocybin (audio)
: a chemical that is obtained from a fungus and causes hallucinations

Medical Definition

psilocybin

noun
psi·​lo·​cy·​bin ˌsī-lə-ˈsī-bən How to pronounce psilocybin (audio)
: a hallucinogenic indole C12H17N2O4P obtained from a basidiomycetous fungus (as Psilocybe mexicana or P. cubensis synonym Stropharia cubensis)

More from Merriam-Webster on psilocybin

Love words? Need even more definitions?

Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free!

More from Merriam-Webster