psilocybin

noun

psi·​lo·​cy·​bin ˌsī-lə-ˈsī-bən How to pronounce psilocybin (audio)
: a hallucinogenic indole C12H17N2O4P obtained from a fungus (such as Psilocybe mexicana or P. cubensis synonym Stropharia cubensis)

Examples of psilocybin in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Tyson’s introduction to psilocybin proved life-altering. Jerel Ezell, STAT, 1 May 2026 Drugs such as psilocybin and MDMA have demonstrated striking results in clinical trials to treat depression, post-traumatic stress disorder and other serious mental health conditions. Leana S. Wen, Washington Post, 28 Apr. 2026 The Natural Medicine Act, which decriminalized psilocybin and greenlit the state's development of a therapeutic pathway for mushrooms, also decriminalized ibogaine and other psychedelics. Olivia Young, CBS News, 24 Apr. 2026 Compass Pathways has been studying a proprietary formulation of synthetic psilocybin for treatment-resistant depression. Jacqueline Howard, CNN Money, 24 Apr. 2026 See All Example Sentences for psilocybin

Word History

Etymology

New Latin Psilocybe, fungus genus + -in entry 1

First Known Use

1958, in the meaning defined above

Time Traveler
The first known use of psilocybin was in 1958

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Cite this Entry

“Psilocybin.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/psilocybin. Accessed 6 May. 2026.

Kids Definition

psilocybin

noun
psi·​lo·​cy·​bin ˌsī-lə-ˈsī-bən How to pronounce psilocybin (audio)
: a chemical that is obtained from a fungus and causes hallucinations

Medical Definition

psilocybin

noun
psi·​lo·​cy·​bin ˌsī-lə-ˈsī-bən How to pronounce psilocybin (audio)
: a hallucinogenic indole C12H17N2O4P obtained from a basidiomycetous fungus (as Psilocybe mexicana or P. cubensis synonym Stropharia cubensis)

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