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In men, the hormone testosterone, which is secreted in high amounts, is converted into dihydrotestosterone (DHT) via the 5-alpha reductase enzyme found in the scalp.—
Levent Daşkıran,
Wired News,
31 May 2026 Although most commonly known for helping lower cholesterol, phytosterols may inhibit 5-alpha-reductase, the enzyme that converts testosterone into DHT (dihydrotestosterone).—
Mykenna Maniece,
Vogue,
19 Mar. 2026 Options include topical or oral minoxidil, antihormonal therapies such as spironolactone (for women), or 5-alpha reductase inhibitors such as finasteride or dutasteride.—
Tom Gavin,
EverydayHealth.com,
17 Feb. 2026 Sold under the brand names Proscar and Propecia among others, finasteride works by blocking the enzyme 5α-reductase, which changes testosterone into dihydrotestosterone (DHT), the hormone that causes AGA hair follicles to shrink.—
Pranjal Malewar,
New Atlas,
18 Oct. 2025 An enzyme called 5-alpha reductase changes the hormone into dihydrotestosterone.—
Rj MacKenzie,
Popular Science,
20 Mar. 2025 Summary Simvastatin and atorvastatin are cholesterol-lowering medications classified as HMG-CoA reductase inhibitors.—
Phuoc Anh (anne) Nguyen, Pharmd, Ms,
Verywell Health,
18 Dec. 2024 Bacterial strains that metabolized bilirubin using bilirubin reductase all came from species that were found to belong to a single clade (the researchers informally referred to it as the bilirubin reductase clade).—
Elizabeth Rayne,
Ars Technica,
27 Jan. 2024