side effect

noun

Synonyms of side effectnext
: a secondary and usually adverse effect (as of a drug)
toxic side effects

called also side reaction

Examples of side effect in a Sentence

Nausea and diarrhea are the side effects of the drug. the harmful side effects of using chemicals to kill insects The merger created positive side effects for both companies.
Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Consumers will be expected to answer 15 questions, covering topics such as their mood, general health, and any side effects from their current medication before receiving their prescription. Will McCurdy, PC Magazine, 4 Apr. 2026 After battling a rare adrenal gland cancer for the past five years, Gilbert had experienced all sorts of side effects that can spring up from treatments and medications. Maya Georgi, Rolling Stone, 4 Apr. 2026 In more severe cases of hair loss, a doctor might prescribe oral minoxidil, which is generally absorbed better by the body but also typically comes with more side effects. Rebecca Strong, USA Today, 3 Apr. 2026 The Lancet published a study in February that should have closed the book on statin side effects. Vikas Patel, STAT, 3 Apr. 2026 See All Example Sentences for side effect

Word History

First Known Use

1814, in the meaning defined above

Time Traveler
The first known use of side effect was in 1814

Browse Nearby Words

Cite this Entry

“Side effect.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/side%20effect. Accessed 5 Apr. 2026.

Kids Definition

side effect

noun
: an often harmful and unwanted effect (as of a drug) that occurs along with the basic desired effect
the environmental side effects of using chemicals to kill pests

Medical Definition

side effect

noun
: a secondary and usually adverse effect (as of a drug)
toxic side effects
a side effect of drowsiness caused by antihistamines

called also side reaction

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