side effect

noun

: a secondary and usually adverse effect (as of a drug)
toxic side effects

called also side reaction

Examples of side effect in a Sentence

Nausea and diarrhea are the side effects of the drug. the harmful side effects of using chemicals to kill insects The merger created positive side effects for both companies.
Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Gastrointestinal Effects By far, the most common side effects patients will have will be gastrointestinal side effects like nausea, vomiting, diarrhea and constipation. Omer Awan, Forbes.com, 17 June 2025 Taking a magnesium supplement by mouth can cause side effects like stomach pain, nausea, and diarrhea. Health, 16 June 2025 What This Means For You Magnesium is essential for your health, but taking too much in supplement form can lead to serious side effects. Abby Norman, Verywell Health, 13 June 2025 The surgery that saved her life last year did leave the girl with some lasting side effects. Nicole Acevedo, NBC news, 12 June 2025 See All Example Sentences for side effect

Word History

First Known Use

1814, in the meaning defined above

Time Traveler
The first known use of side effect was in 1814

Browse Nearby Words

Cite this Entry

“Side effect.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/side%20effect. Accessed 20 Jun. 2025.

Kids Definition

side effect

noun
: an often harmful and unwanted effect (as of a drug) that occurs along with the basic desired effect
the environmental side effects of using chemicals to kill pests

Medical Definition

side effect

noun
: a secondary and usually adverse effect (as of a drug)
toxic side effects
a side effect of drowsiness caused by antihistamines

called also side reaction

Last Updated: - Updated example sentences
Love words? Need even more definitions?

Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free!