simvastatin

noun

sim·​va·​stat·​in ˈsim-və-ˌsta-tᵊn How to pronounce simvastatin (audio) ˌsim-və-ˈsta- How to pronounce simvastatin (audio)
: a semisynthetic drug C25H38O5 that decreases the level of cholesterol in the bloodstream and is derived from a compound produced by a mold (Aspergillus terreus)

Examples of simvastatin in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
The study looked at the effects of five drugs − atorvastatin, fluvastatin, pravastatin, rosuvastatin and simvastatin − and used data from over a dozen trials of at least 1,000 participants each, often comparing the statin versus a placebo. Sara Moniuszko, USA Today, 6 Feb. 2026 For example, cholesterol-lowering drugs like atorvastatin and simvastatin all end in -statin. Scott Lafee, San Diego Union-Tribune, 16 Sep. 2025 Drinking hibiscus tea can speed up your body's elimination of simvastatin, significantly reducing your exposure to the drug. Sarah Bence, Verywell Health, 10 Sep. 2025 Patients can obtain low-dose simvastatin without a prescription, but the medications are placed behind the pharmacy counter and distributed after a pharmacist’s consultation. Joshua Cohen, Forbes, 2 Mar. 2024 For example, a daily glass of this juice boosts simvastatin and lovastatin by 260% if taken at the same time (American Journal of Medicine, January 2016). Joe Graedon, M.s., and Teresa Graedon, oregonlive, 27 Feb. 2023

Word History

Etymology

sim- (probably alteration of synthetic) + lovastatin

First Known Use

1987, in the meaning defined above

Time Traveler
The first known use of simvastatin was in 1987

Browse Nearby Words

Cite this Entry

“Simvastatin.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/simvastatin. Accessed 6 Jul. 2026.

Medical Definition

simvastatin

noun
sim·​va·​stat·​in ˈsim-və-ˌstat-ᵊn How to pronounce simvastatin (audio) ˌsim-və-ˈstat- How to pronounce simvastatin (audio)
: a statin drug C25H38O5 that inhibits the synthesis of cholesterol, is used orally to lower high levels of cholesterol in the blood, and is derived from a compound produced by a mold of the genus Aspergillus (A. terreus)

Note: Simvastatin is marketed under the trademarks Vytorin and Zocor.

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