statin

noun

stat·​in ˈsta-tᵊn How to pronounce statin (audio)
: any of a group of drugs (such as lovastatin and simvastatin) that inhibit the synthesis of cholesterol and promote the production of LDL-binding receptors in the liver resulting in a usually marked decrease in the level of LDL and a modest increase in the level of HDL circulating in blood plasma

Examples of statin in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
For example, vitamin D, sometimes taken to support the heart, may reduce the efficacy of statins. Sarah Cottone, Health, 24 Feb. 2025 Some common statins used to control high cholesterol can build up to toxic levels because the chemical in grapefruit juice blocks its normal processing. Gary W. Miller, The Conversation, 3 Feb. 2025 Similarly, simvastatin and atorvastatin might be able to be swapped out for other statins like fluvastatin, pravastatin, and rosuvastatin. Caroline Tien, SELF, 7 Apr. 2025 For one, the researchers excluded participants who started or stopped cholesterol-lowering drugs such as statins during the course of the study. Brian Mastroianni, Health, 7 Feb. 2025 See All Example Sentences for statin

Word History

Etymology

from -statin (as in lovastatin)

First Known Use

1985, in the meaning defined above

Time Traveler
The first known use of statin was in 1985

Browse Nearby Words

Cite this Entry

“Statin.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/statin. Accessed 29 Apr. 2025.

Medical Definition

statin

noun
stat·​in ˈstat-ᵊn How to pronounce statin (audio)
: any of a group of lipid-lowering drugs (as lovastatin and simvastatin) that function by inhibiting a liver enzyme which controls the synthesis of cholesterol and by promoting the production of LDL-binding receptors in the liver resulting in a usually marked decrease in the level of LDL and a modest increase in the level of HDL circulating in blood plasma

More from Merriam-Webster on statin

Last Updated: - Updated example sentences
Love words? Need even more definitions?

Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free!