tamoxifen

noun

ta·​mox·​i·​fen tə-ˈmäk-sə-ˌfen How to pronounce tamoxifen (audio)
: an estrogen antagonist C26H29NO used in the form of its citrate especially to treat postmenopausal breast cancer

Examples of tamoxifen in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
After a moment’s thought, Greenwald told her to do the lumpectomy—and the tamoxifen, which would cut the chance of cancer recurrence in half. Melanie Thernstrom, New Yorker, 29 June 2026 If the findings are confirmed, the risk score could help doctors tailor recommendations for surveillance intensity and risk-reduction strategies, including medications like tamoxifen or aromatase inhibitors, specifically for those high-risk women, says Roy. Emily Kay Votruba, EverydayHealth.com, 2 Oct. 2025 In general, though, the risk of uterine cancer from tamoxifen use is low. Carrie Madormo, Health, 13 July 2025 Thank you, Dora, on behalf of all the women tamoxifen has helped, and all the women tamoxifen will help. Katie Hafner, Scientific American, 31 Oct. 2024 See All Example Sentences for tamoxifen

Word History

Etymology

probably by recombination & alteration of trans-, oxy, and clomiphene

First Known Use

1972, in the meaning defined above

Time Traveler
The first known use of tamoxifen was in 1972

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Cite this Entry

“Tamoxifen.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/tamoxifen. Accessed 7 Jul. 2026.

Medical Definition

tamoxifen

noun
ta·​mox·​i·​fen ta-ˈmäk-si-ˌfen How to pronounce tamoxifen (audio)
: a selective estrogen receptor modulator that acts as an estrogen antagonist in breast tissue and is administered orally in the form of its citrate C26H29NO·C6H8O7 especially to treat breast cancer or reduce the risk of its development or reoccurrence see nolvadex

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