tryptophan

noun

tryp·​to·​phan ˈtrip-tə-ˌfan How to pronounce tryptophan (audio)
variants or less commonly tryptophane
: a crystalline essential amino acid C11H12N2O2 that is widely distributed in proteins

Examples of tryptophan in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Avoid stimulants and instead include foods rich in tryptophan, such as banana, a glass of warm milk with a little honey, or a handful of almonds. Mónica Heras, Vogue, 30 Dec. 2025 Ounce for ounce, turkey contains less tryptophan—an amino acid popularly blamed for post-Thanksgiving sleepiness—than cheddar cheese or an octopus does. The Atlantic Science Desk, The Atlantic, 27 Dec. 2025 According to Mack, foods that contain tryptophan, magnesium or compounds that support melatonin production may have a stronger connection to sleep. Khloe Quill, FOXNews.com, 21 Dec. 2025 Milk contains tryptophan and calcium, which help the body make sleep-regulating hormones like serotonin and melatonin. Lindsey Desoto, Health, 28 Nov. 2025 See All Example Sentences for tryptophan

Word History

Etymology

borrowed from German Tryptophan, from tryptisch tryptic + -o- -o- + -phan -phane

First Known Use

1890, in the meaning defined above

Time Traveler
The first known use of tryptophan was in 1890

Browse Nearby Words

Cite this Entry

“Tryptophan.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/tryptophan. Accessed 31 Dec. 2025.

Kids Definition

tryptophan

noun
tryp·​to·​phan ˈtrip-tə-ˌfan How to pronounce tryptophan (audio)
: an amino acid that is found in many proteins and is necessary for life but cannot be manufactured by the human body and must be obtained in food

Medical Definition

tryptophan

noun
tryp·​to·​phan ˈtrip-tə-ˌfan How to pronounce tryptophan (audio)
variants also tryptophane
: a crystalline essential amino acid C11H12N2O2 that is widely distributed in proteins
abbreviation Trp

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