Synonyms of virulencenext
: the quality or state of being virulent: such as
a
: extreme bitterness or malevolence : rancor
the virulence of their hatred
She said the rising virulence of the rhetoric against Muslims has flooded her with sadness, grief, alienation and fear.Laura DaSilva
But the virulence of the campaign, on both sides … provides a clue to the deeper forces at work: the polarizing of politics in a traditionally moderate place.The Economist
b
: the relative capacity of a pathogen (such as a bacterium or virus) to overcome a host's defenses and cause disease or damage : the degree of pathogenicity of a causative agent of disease
a bacterial strain of low virulence
the virulence of a novel virus
also : the ability to overcome a host's defenses and cause disease or damage : the state of being pathogenic
With its newly acquired virulence, this otherwise mild-mannered avian influenza virus went wild. Rick Weiss
c
: relative severity or malignancy
Breast cancer is as diverse as the breast itself, appearing in many different guises. Some cancers seem to erupt out of ordinary breast tissue with an awesome virulence, spreading rapidly throughout the body.David Plotkin

Examples of virulence in a Sentence

I was surprised by the virulence of the criticism.
Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Firefighters and authorities in both European countries were caught off guard by the virulence of the fires, which were fueled by high temperatures and the long-term effects of climate change. ABC News, 25 July 2026 In this case, some variants become more resistant to the treatment, but the resistance comes at a cost—slower growth or less virulence, for example. Beth Mole, ArsTechnica, 23 July 2026 Flu has overtaken covid in infections and hospitalizations during the winter respiratory virus season, and their virulence is becoming similar. Fenit Nirappil, Washington Post, 4 Mar. 2026 Genes involved in adaptation, such as those linked to virulence, metabolism or host interaction, also move with them. Lily Peck, The Conversation, 17 Feb. 2026 See All Example Sentences for virulence

Word History

Etymology

borrowed from French & Latin; borrowed from French, going back to Middle French, borrowed from Late Latin vīrulentia "poisonous odor, infection," from Latin vīrulentus "full of poison, venomous" + -ia -ia entry 1 — more at virulent

First Known Use

1597, in the meaning defined above

Time Traveler
The first known use of virulence was in 1597

Browse Nearby Words

Cite this Entry

“Virulence.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/virulence. Accessed 31 Jul. 2026.

Kids Definition

: the quality or state of being virulent

Medical Definition

: the quality or state of being virulent: as
a
: the relative capacity of a pathogen (as a bacterium or virus) to overcome a host's defenses and cause disease or damage : the degree of pathogenicity of a causative agent of disease
a bacterial strain of low virulence
attempted to determine the virulence of the newly identified virus
also : the ability to overcome a host's defenses and cause disease or damage : the state of being pathogenic
With its newly acquired virulence, this otherwise mild-mannered avian influenza virus went wild. Rick Weiss
b
: relative severity or malignancy
ameliorate the virulence of a disease

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