cocaine

noun

co·​caine kō-ˈkān How to pronounce cocaine (audio)
ˈkō-ˌkān
: a bitter crystalline alkaloid C17H21NO4 obtained from coca leaves that is used especially in the form of its hydrochloride medically as a topical anesthetic and illicitly for its euphoric effects and that may result in a compulsive psychological need

Examples of cocaine in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
The investigation led to authorities identifying an individual who was trafficking fentanyl and cocaine in the Naugatuck Valley as Muniz, officials said. — Justin Muszynski, Hartford Courant, 25 July 2026 While the prerequisite Miami bachelor party antics — party buses, yacht parties, and accidentally stealing 30 kilos of cocaine from a cartel boss — all occur, the film tries to root itself in some real pathos about the nature of male friendships. — Christian Zilko, IndieWire, 24 July 2026 Australia midfielder Cristian Volpato has allegedly tested positive for cocaine after being caught twice for speeding in Sydney, according to media reports. — Sam Joseph, New York Times, 24 July 2026 He was subjected to a roadside drug test which returned a positive result for cocaine, police said in a statement on Friday. — ABC News, 24 July 2026 See All Example Sentences for cocaine

Word History

First Known Use

1860, in the meaning defined above

Time Traveler
The first known use of cocaine was in 1860

Phrases Containing cocaine

Rhymes for cocaine

See All Rhymes for cocaine

Browse Nearby Words

coca
cocaine
cocaine family
See all Nearby Words

Cite this Entry

“Cocaine.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/cocaine. Accessed 31 Jul. 2026.

Copy Citation

Kids Definition

cocaine

noun
co·​caine kō-ˈkān How to pronounce cocaine (audio)
ˈkō-ˌkān
: a bitter habit-forming drug obtained from coca leaves and used in medicine to deaden pain and illegally for its euphoric effects

Medical Definition

cocaine

noun
co·​caine kō-ˈkān, ˈkō-ˌ How to pronounce cocaine (audio)
: a bitter crystalline alkaloid C17H21NO4 obtained from coca leaves that is used medically especially in the form of its hydrochloride C17H21NO4·HCl as a topical anesthetic and illicitly for its euphoric effects and that may result in a compulsive psychological need

More from Merriam-Webster on cocaine

Nglish: Translation of cocaine for Spanish Speakers

Britannica.com: Encyclopedia article about cocaine

Last Updated: - Updated example sentences
Love words? Need even more definitions?

Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free!

More from Merriam-Webster

Word of the Day

Listen to the pronunciation of comely

See Definitions and Examples »

Popular in Grammar & Usage

See More

7 Pairs of Commonly Confused Words

Merriam-Webster’s Great Big List of Words You Love to Hate

Is it 'nerve-racking' or 'nerve-wracking'?

Why does English have so many silent letters?

Your vs. You're: How to Use Them Correctly
See More

Popular in Wordplay

See More

Dutch Treat and French Leave: Eight Place-Based Compounds

14 Phobias You Probably Haven't Heard Of

The Longest Long Words List

The Words of the Week - Jul. 31

Even More Bird Names that Sound Like Insults (and Sometimes Are)
See More

Popular

See More

7 Pairs of Commonly Confused Words

Dutch Treat and French Leave: Eight Place-Based Compounds

14 Phobias You Probably Haven't Heard Of
See More

Games & Quizzes

See All
Play Quordle: Guess all four words in a limited number of tries. Each of your guesses must be a real 5-letter word.
Quordle Can you solve 4 words at once?
Play Blossom: Solve today's spelling word game by finding as many words as you can using just 7 letters. Longer words score more points.
Blossom Pick the best words!
Play Missing Letter: a crossword with a twist. Each of the 25 puzzle words start with a different letter of the alphabet. Which letter is missing?
The Missing Letter A daily crossword with a twist
chain-question-mark
Missing Link Quiz July 2026 Five seconds to figure out the word that fits bot...
See All