nicotine

noun

nic·​o·​tine ˈni-kə-ˌtēn How to pronounce nicotine (audio)
: a poisonous alkaloid C10H14N2 that is the chief active principle of tobacco and is used as an insecticide

Examples of nicotine in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Medical research has shown that common side effects of GLP-1s are dampened cravings for alcohol, nicotine and opioids. Melissa Ruggieri, USA Today, 30 Dec. 2025 Ammonia, which can cause nose, throat and respiratory tract irritation, is often added to tobacco products to increase the body’s absorption of nicotine and make tobacco more additive, the US Food and Drug Administration states on its website. Sandee Lamotte, CNN Money, 29 Dec. 2025 For instance, mouse fathers exposed to nicotine sire male pups with livers that are good at disarming not just nicotine but cocaine and other toxins as well. Ivan Amato, Quanta Magazine, 22 Dec. 2025 Yet on tobacco and nicotine, some want to move Massachusetts in the opposite direction. Peter Brennan, Boston Herald, 17 Dec. 2025 See All Example Sentences for nicotine

Word History

Etymology

French, from New Latin nicotiana

First Known Use

1817, in the meaning defined above

Time Traveler
The first known use of nicotine was in 1817

Cite this Entry

“Nicotine.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/nicotine. Accessed 5 Jan. 2026.

Kids Definition

nicotine

noun
nic·​o·​tine ˈnik-ə-ˌtēn How to pronounce nicotine (audio)
: a poisonous substance found in tobacco and used as an insecticide

Medical Definition

nicotine

noun
nic·​o·​tine ˈnik-ə-ˌtēn How to pronounce nicotine (audio)
: a poisonous alkaloid C10H14N2 that is the chief active principle of tobacco and that is used as an insecticide and is sometimes used in smoking cessation aids

Note: Trademarks for nicotine include Nicoderm, Nicorette, and Nicotrol.

More from Merriam-Webster on nicotine

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