side effect

noun

: a secondary and usually adverse effect (as of a drug)
toxic side effects

called also side reaction

Examples of side effect in a Sentence

Nausea and diarrhea are the side effects of the drug. the harmful side effects of using chemicals to kill insects The merger created positive side effects for both companies.
Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Mild side effects, like headache, pain at the injection site, fever, and nausea, are common.13 The Pfizer Abrysvo and Moderna mResvia vaccines have been FDA-approved for high-risk adults under 50. Stephanie Brown, Verywell Health, 4 Aug. 2025 Children can suffer side effects from common shots like the MMR vaccine, ranging from mild symptoms like a rash or fever to rare fatal complications. ArsTechnica, 4 Aug. 2025 Breast cancer treatment and side effects, including menopause Klimpl lives in San Diego but is a Hawaii native. David Oliver, USA Today, 31 July 2025 Consuming too much caffeine can also lead to side effects like anxiety, rapid heartbeat, agitation, and trouble sleeping. Jillian Kubala, Health, 31 July 2025 See All Example Sentences for side effect

Word History

First Known Use

1814, in the meaning defined above

Time Traveler
The first known use of side effect was in 1814

Browse Nearby Words

Cite this Entry

“Side effect.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/side%20effect. Accessed 10 Aug. 2025.

Kids Definition

side effect

noun
: an often harmful and unwanted effect (as of a drug) that occurs along with the basic desired effect
the environmental side effects of using chemicals to kill pests

Medical Definition

side effect

noun
: a secondary and usually adverse effect (as of a drug)
toxic side effects
a side effect of drowsiness caused by antihistamines

called also side reaction

Last Updated: - Updated example sentences
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