How to Use epigenome in a Sentence

epigenome

noun
  • During methylation, a methyl group in the epigenome turns genes off.
    — Tad Friend, New Yorker, 4 Aug. 2025
  • David had long suspected that the epigenome was central to longevity.
    — Margaret Talbot, The New Yorker, 11 Aug. 2021
  • Sinclair therefore focused on another part of the genome, called the epigenome.
    — Alice Park, Time, 12 Jan. 2023
  • The researchers who have developed base editing even dream of reaching into the epigenome.
    — The Economist, 26 Oct. 2017
  • The epigenome itself is controlled by agents that add or subtract chemical groups, known as marks, to its proteins.
    — Tad Friend, The New Yorker, 24 Mar. 2017
  • Likewise, alterations to the epigenome, which controls which genes are turned on and off, can cause cells to read the wrong genes and lose their function over time.
    — Lori Miller Kase, Discover Magazine, 9 Apr. 2022
  • Could the team activate telomerase to rejuvenate the epigenome?
    — Margaret Talbot, The New Yorker, 11 Aug. 2021
  • Adverse events while one is in utero may affect one’s epigenome, a set of chemical compounds that tell the genome what to do and regulates aging.
    — Byerin Prater, Fortune, 10 Nov. 2022
  • Since all cells have the same DNA blueprint, the epigenome is what makes skin cells turn into skin cells and brain cells into brain cells.
    — Alice Park, Time, 12 Jan. 2023
  • That is, in the epigenome, a landscape of proteins and chemicals that sits atop your genetic material.
    — Sonya Collins, Fortune Well, 23 Feb. 2023
  • To do this, Sinclair’s team developed ICE, short for inducible changes to the epigenome.
    — Sandee Lamotte, CNN, 12 Jan. 2023
  • Together the methyl groups and coiling proteins—what scientists call the epigenome—are essential for the brain to become a brain in the first place.
    — Carl Zimmer, Discover Magazine, 12 Apr. 2023
  • The epigenome, influenced by lifestyle choices, presents a reversible level of genetic fine-tuning.
    — Salvatore Viscomi, Forbes, 22 Mar. 2023
  • The epigenome, a kind of cellular operating system, regulates which genes are turned on, or expressed, and which turned off, or not expressed.
    — Robert Weisman, BostonGlobe.com, 12 Jan. 2023
  • Environmental factors such as diet, stress, and sun exposure can affect the epigenome.
    — Marcia Desanctis, Vogue, 21 July 2018
  • Reina-Campos is wondering whether T cells could use their own epigenome as a metabolic depot to fuel their functions.
    — Noah Lyons, San Diego Union-Tribune, 28 Jan. 2025
  • Kellis led the data analysis team, which applied machine-learning algorithms to decode the language of the epigenome.
    — Dan Ferber, Discover Magazine, 30 Nov. 2015
  • The key is to manipulate the body’s epigenome—a sort of cellular keyboard that determines which underlying genetic notes get played and which don’t.
    — Time Contributors, Time, 27 Apr. 2026
  • Our environment can rework our epigenome, and some studies suggest that this reworking may produce long-term changes in personality.
    — Carl Zimmer, Discover Magazine, 17 June 2010
  • Sinclair theorizes that epigenomes may provide an in for scientists to intervene in the aging process, due to their connections with bodily functions.
    — Katie Liu, Discover Magazine, 3 Feb. 2025
  • Cells treated with Yamanaka factors, erases marks on the epigenome, losing their identity thus the reversal to the embryonic state (stem cell).
    — Stephen Ibaraki, Forbes, 13 May 2022
  • The team initially studied how a somatic cell epigenome transformed during the reprogramming process and figured out the exact moment aberrations emerged.
    — Darren Orf, Popular Mechanics, 17 Aug. 2023
  • Penick said the Indian jumping ant colonies used in the study were the same ones that were collected in India almost 20 years ago and were the first epigenome for the species sequenced.
    — NBC News, 14 Apr. 2021
  • In the past decade, researchers have focused on the epigenome, a host of factors—some heritable—that influence how genetic information is copied and read at the cellular level.
    — Byandrew Curry, science.org, 27 Feb. 2025
  • Neretti focuses on the epigenome, looking for changes in DNA organization in the nucleus and which genes are turned on or off in senescent and normal cells.
    — Monique Brouillette, Popular Mechanics, 21 Feb. 2023
  • Skinner's own research in animals suggests changes to the epigenome, a swirl of biological factors that affect how genes are expressed, can be passed down through multiple generations.
    — Andrew Curry, Science | AAAS, 18 July 2019
  • During fetal development, chemical triggers called epigenomes cause cells to differentiate, so that some become muscle and others become bone, nerves, skin, or tissue.
    — Anya Groner, Longreads, 9 June 2017
  • The Stanford approach utilizes powerful agents known as Yamanaka factors, which reprogram a cell’s epigenome to its time zero, or embryonic state.
    — Nicholas Wade, New York Times, 24 Mar. 2020
  • Hitting the right spot on the epigenome essentially closed off the APOE4 gene, limiting its expression in mice, the researchers reported.
    — Andrew Joseph, STAT, 16 July 2023
  • David published a great paper in Nature late last year showing that in mice Yamanaka gene therapy can safety reprogram the epigenome of the retina and restore vision in a mouse model of glaucoma.
    — Alex Zhavoronkov, Forbes, 14 June 2021

Some of these examples are programmatically compiled from various online sources to illustrate current usage of the word 'epigenome.' Any opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback about these examples.

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