How to Use monoclonal in a Sentence

monoclonal

1 of 2 adjective
  • Next week, the government will have to cut shipments of monoclonal-antibody treatments by a third.
    — Ed Yong, The Atlantic, 17 Mar. 2022
  • The most common of these are a type of cancer drug called monoclonal antibodies, proteins that bind to and kill tumor cells.
    — Tom Anchordoquy, The Conversation, 17 June 2022
  • The new course of monoclonal antibodies are meant to prevent a new case, which could be devastating for him.
    — Madeline Buckley, chicagotribune.com, 12 Feb. 2022
  • And even now, while vaccines and antivirals still work against them, monoclonal antibodies do not.
    — Karen Weintraub, USA TODAY, 4 Jan. 2023
  • Already, some monoclonal antibody treatments were rendered useless and had to be abandoned as the virus evolved.
    — Andrew Joseph, STAT, 11 Oct. 2022
  • Sotrovimab is a monoclonal antibody therapy for the same group of patients.
    — Melissa Healy, Los Angeles Times, 1 Feb. 2022
  • At the same time, monoclonal antibody treatment supplies distributed to states each week has been cut by 35%.
    — Karen Travers, ABC News, 30 Mar. 2022
  • The monoclonal antibodies that can be used against the Omicron variant are sotrovimab and bebtelovimab.
    — Los Angeles Times, 25 Mar. 2022
  • The jury is still out on how severe these strains are, but there are early reports that monoclonal antibody treatments, reserved for high-risk patients, can’t stand up to them.
    — Erin Prater, Fortune, 22 Oct. 2022
  • While the variant does seem to have evaded some drugs called monoclonal antibodies, antiviral drugs are thought to still have efficacy.
    — Paul Sisson, San Diego Union-Tribune, 23 Mar. 2022
  • White and insured people have accessed monoclonal antibodies at far higher rates than the uninsured and people of color.
    — Natalie Shure, The New Republic, 8 Mar. 2022
  • Last month the White House began cutting back shipments of monoclonal antibody treatments to states to make supplies last longer.
    — Zeke Miller, Chron, 25 Apr. 2022
  • Last month, the White House began cutting back shipments of monoclonal antibody treatments to states to make supplies last longer.
    — CBS News, 26 Apr. 2022
  • Some of the monoclonal antibodies made to give people passive immunity against the virus have also stopped working against the new variants.
    — Brenda Goodman, CNN, 1 Sep. 2022
  • Right now, both the antivirals and the monoclonal antibody treatment that works against omicron are in extremely short supply, and they are reserved for those at highest risk.
    — Melody Schreiber, The New Republic, 25 Jan. 2022
  • Efforts have ranged from conserving monoclonal antibodies and Paxlovid when supplies were low, to now dealing with contrast dye.
    — Jessica Bartlett, BostonGlobe.com, 5 June 2022
  • Hospitals nationwide have been forced to ration doses of the sotrovimab monoclonal antibody treatment for their most at-risk patients.
    — Denise Roland, WSJ, 21 Jan. 2022
  • It also should not be thought of as an alternative to effective treatments, such as some monoclonal antibodies or Paxlovid.
    — Dr. Keith Roach, oregonlive, 23 Mar. 2022
  • Thirty-six of the mutations were to the virus's spike proteins, which cover the outside of the virus and are the main targets of vaccines and treatments like monoclonal antibodies.
    — NBC News, 28 Jan. 2022
  • Another injectable drug, Bebtelovimab, is a monoclonal antibody and can be given to those age 12 and older who weight at least 88 pounds.
    — Luke Money, Los Angeles Times, 30 June 2022
  • One of Omicron’s most salient features is how resistant the variant family is to vaccines and most monoclonal antibodies.
    — William A. Haseltine, Forbes, 6 May 2022
  • The President said the administration's supply of monoclonal antibodies will start to run out by the end of May.
    — Kate Sullivan, CNN, 30 Mar. 2022
  • Research to date suggests that monoclonal antibodies can reduce the risk of hospitalization and death by up to 80% compared to people who don’t take the drugs.
    — Alice Park, Time, 20 Apr. 2022
  • First, using more [of the monoclonal-antibody treatment] Evusheld—which is a very, very effective tool for people who are immunocompromised.
    — Dhruv Khullar, The New Yorker, 18 June 2022
  • Perhaps the biggest hurdle in getting the antiviral pills to the public is the fact that pharmacists cannot prescribe the pills -- unlike monoclonal antibody infusion treatments.
    — Jeannie Roberts, Arkansas Online, 17 Apr. 2022
  • Since the start of the pandemic, Anderson said, the protease had changed 10 times as slowly as the spike protein that vaccines and monoclonal antibodies target.
    — Jason Mast, STAT, 29 May 2022
  • To keep people out of the hospital, the Health Wagon had been treating people with Covid-19 with monoclonal antibodies.
    — Julie Wernau, WSJ, 15 Jan. 2022
  • In the case of two children awaiting transplants, they were being treated with monoclonal antibodies — authorized for those 12 and older — to slow down the disease process and intravenous remdesivir to help clear it.
    — Los Angeles Times, 24 Jan. 2022

monoclonal

2 of 2 noun
  • This is typically done through serum and urine tests to detect abnormal free light chains and monoclonal proteins.
    — Patty Weasler, Verywell Health, 5 Aug. 2025
  • The monoclonal version with just one strain outperformed each of the bivalent options.
    — Claire Bugos, Verywell Health, 16 June 2023
  • This stands in contrast to the Zaire strain of the virus, where there are two vaccines licensed as well as monoclonal antibodies.
    — Gabrielle Emanuel, NPR, 20 May 2026
  • Tozorakimab and rival drugs belong to a class of treatments called monoclonal antibodies.
    — Elsa Ohlen, CNBC, 27 Mar. 2026
  • But monoclonal treatments are also pricey, and different combinations of antibodies would still be required for each snake species.
    — Cassandra Willyard, Scientific American, 19 Sep. 2023
  • The monoclonal has already undergone a Phase 1 safety trial.
    — Theresa Gaffney, STAT, 23 June 2026
  • This monoclonal could be a notable measure of protection for babies, wherever it's approved, available and accessible to those who need it.
    — Sasha Pezenik, ABC News, 4 Nov. 2022
  • But in some people living with MS, the disease progresses despite monoclonal treatment.
    — Byjennifer Couzin-Frankel, science.org, 14 Nov. 2024
  • In multiple myeloma, cancerous plasma cells make abnormal proteins called monoclonal light chains.
    — Lindsay Curtis, Health, 14 Sep. 2025
  • But for that to work, the monoclonal has to be very highly effective, and to be that effective, the antibodies need to be specific enough to the strain of malaria that’s circulating.
    — Dylan Matthews, Vox, 7 Dec. 2018
  • Watson, a co-author of the new study, also notes that ALZ may have benefits beyond those seen with monoclonal antibodies.
    — Jon Hamilton, NPR, 29 Oct. 2025
  • Also, the monoclonal antibodies work primarily by breaking down sticky amyloid plaques.
    — Jon Hamilton, NPR, 29 Oct. 2025
  • Someone had to be inside the White House making sure that resources were made appropriately to expand testing, to expand monoclonal and develop vaccines, and that was part of my role.
    — ABC News, 29 Aug. 2023
  • From this analysis, researchers were able to calculate the 75% reduction in infection risk if the monoclonal matched the local HIV strain.
    — Jon Cohen, Science | AAAS, 26 Jan. 2021
  • Even so, Langbaum thinks people with the APOE4/4 genes can be treated safely with the current monoclonal antibodies.
    — Jon Hamilton, NPR, 29 Oct. 2025
  • Treatment for anthrax includes antibiotics and monoclonal antibodies.
    — Hannah Kinzer, The Conversation, 25 Mar. 2026
  • Some studies suggest that the presence of various inflammatory factors may explain the fluid leakage from capillaries during SCLS episodes, and that people who have the disease may have a low amount of monoclonal or M protein in their blood.
    — Lauren Linder, CBS News, 14 Jan. 2026
  • Høeg pointed to the number of deaths of babies who received the RSV monoclonals in clinical trials, despite study investigators and the FDA determining the deaths appeared to be unrelated to the products.
    — O. Rose Broderick, STAT, 20 Feb. 2026
  • Their discovery opened the door to genetic engineering, gene therapy, identifying human remains and criminal suspects from DNA samples, tracing family trees via DNA, and monoclonal antibodies.
    — David Morgan, CBS News, 8 Nov. 2025

Some of these examples are programmatically compiled from various online sources to illustrate current usage of the word 'monoclonal.' Any opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback about these examples.

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